Rabbit ribosomal protein SA Polyclonal Antibody | anti-RPSA antibody

Rabbit anti-human ribosomal protein SA polyclonal Antibody

Cat. Num. AAA81101

• Gene Names: RPSA; SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
• Applications: Western Blot, ELISA
• Purity: Antigen Affinity purified
• Synonyms: ribosomal protein SA, Antibody; Rabbit anti-human ribosomal protein SA polyclonal Antibody; ribosomal protein SA; RPSA; 37LRP; 67LR; LAMBR; LAMR1; LRP; p40Laminin receptor; 37/67 kDa laminin receptor; LRP/LR; LBP/p40; anti-RPSA antibody

• Host: Rabbit
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Antigen Affinity purified
• Sequence Length: 295

• Applicable Applications for anti-RPSA antibody: WB (Western Blot), ELISA
• Immunogen: Human LAMR1,RPSA
• Storage Buffer: PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
• Species Reactivity: Human, Mouse, Rat
• Product Type: Purified Rabbit Anti human PolyClonal Antibody
• Immunogen Species: Homo sapiens (Human)
• Target Names: RPSA
• Target Details: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, nonintegrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosomeassociated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
• Preparation and Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Related Product Information for anti-RPSA antibody

Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, nonintegrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosomeassociated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 14250794
• NCBI GeneID: 3921
• UniProt Accession #: P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0
• NCBI Official Full Name: Ribosomal protein SA
• NCBI Official Synonym Full Names: ribosomal protein SA
• NCBI Official Symbol: RPSA
• NCBI Official Synonym Symbols: SA; LBP; LRP; p40; 67LR; ICAS; lamR; 37LRP; LAMBR; LAMR1; LRP/LR; LBP/p40; NEM/1CHD4
• NCBI Protein Information: 40S ribosomal protein SA; 67LR; RPSA; lamR; 37LRP; LRP/LR; LBP/p40; 37 kDa laminin receptor; 67 kDa laminin receptor; 37/67 kDa laminin receptor; laminin-binding protein precursor p40; colon carcinoma laminin-binding protein; laminin receptor 1 (67kD, ribosomal protein SA); multidrug resistance-associated protein MGr1-Ag
• UniProt Protein Name: 40S ribosomal protein SA
• UniProt Gene Name: RPSA
• UniProt Entry Name: RSSA_HUMAN