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product-image-AAA304661_IHC13.gif IHC (Immunohiostchemistry) (Immunohistochemistry of Rim3 in human brain tissue with Rim3 antibody at 2.5 ug/mL.)

Rabbit anti-Human, Mouse Rim3 Polyclonal Antibody | anti-Rim3 antibody

Rim3 Antibody

Gene Names
RIMS3; NIM3; RIM3
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Rim3, Antibody; Rim3 Antibody; Rab3-interacting molecule 3, regulating synaptic membrane exocytosis 3, RIM3 gamma, RIMS3, NIM3; anti-Rim3 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
This antibody is predicted to have no cross-reactivity to other Rim proteins.
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
308
Applicable Applications for anti-Rim3 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the amino terminus of human Rim3.
Target Name
Rim3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IHC (Immunohiostchemistry)

(Immunohistochemistry of Rim3 in human brain tissue with Rim3 antibody at 2.5 ug/mL.)

product-image-AAA304661_IHC13.gif IHC (Immunohiostchemistry) (Immunohistochemistry of Rim3 in human brain tissue with Rim3 antibody at 2.5 ug/mL.)

WB (Western Blot)

(Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.)

product-image-AAA304661_WB15.gif WB (Western Blot) (Western blot analysis of Rim3 in human brain tissue lysate with Rim3 antibody at 1 ug/mL in the (A) absence and (B) presence of blocking peptide.)
Related Product Information for anti-Rim3 antibody
Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity. While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3. Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis. Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.
Product Categories/Family for anti-Rim3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
15,898 Da
NCBI Official Full Name
regulating synaptic membrane exocytosis protein 3
NCBI Official Synonym Full Names
regulating synaptic membrane exocytosis 3
NCBI Official Symbol
RIMS3
NCBI Official Synonym Symbols
NIM3; RIM3
NCBI Protein Information
regulating synaptic membrane exocytosis protein 3
UniProt Protein Name
Regulating synaptic membrane exocytosis protein 3
UniProt Gene Name
RIMS3
UniProt Synonym Gene Names
KIAA0237; Nim3; RIM 3
UniProt Entry Name
RIMS3_HUMAN

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Product Notes

The Rim3 rims3 (Catalog #AAA304661) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rim3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Rim3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the Rim3 rims3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Rim3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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