IF (Immunofluorescence)
(Immunofluorescent analysis of PC3 cells using AAA119079 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
Rabbit anti-Human RNF31 Polyclonal Antibody | anti-RNF31 antibody
RNF31 Antibody
Gene Names
RNF31; HOIP; ZIBRA
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
>95%, Protein G Purified
Synonyms
RNF31, Antibody; RNF31 Antibody; E3 ubiquitin-protein ligase RNF31 (EC:6.3.2.-); RNF31; ZIBRA; HOIL-1-interacting protein; HOIP; RING finger protein 31; Zinc in-between-RING-finger ubiquitin-associated domain protein; anti-RNF31 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
>95%, Protein G Purified
Sequence Length
921
Applicable Applications for anti-RNF31 antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human E3 ubiquitin-protein ligase RNF31 protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IF (Immunofluorescence)
(Immunofluorescent analysis of PC3 cells using AAA119079 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IF (Immunofluorescence)
(Immunofluorescent analysis of PC3 cells using AAA119079 at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L))
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human kidney tissue using AAA119079 at dilution of 1:100)
IHC (Immunohistochemistry)
(Immunohistochemistry of paraffin-embedded human kidney tissue using AAA119079 at dilution of 1:100)
Related Product Information for anti-RNF31 antibody
E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation. LUBAC conjugates linear polyubiquitin to IKBKG and RIPK1 and is involved in activation of the canonical NF-kappa-B and the JNK signaling pathways. Linear ubiquitination mediated by the LUBAC complex interferes with TNF-induced cell death and thereby prevents inflammation. LUBAC is proposed to be recruited to the TNF-R1 signaling complex (TNF-RSC) following polyubiquitination of TNF-RSC components by BIRC2 and/or BIRC3 and to conjugate linear polyubiquitin to IKBKG and possibly other components contributing to the stability of the complex. Together with FAM105B/otulin, the LUBAC complex regulates the canonical Wnt signaling during angiogenesis. Binds polyubiquitin of different linkage types.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
102,496 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF31 isoform 2
NCBI Official Synonym Full Names
ring finger protein 31
NCBI Official Symbol
RNF31
NCBI Official Synonym Symbols
HOIP; ZIBRA
NCBI Protein Information
E3 ubiquitin-protein ligase RNF31
UniProt Protein Name
E3 ubiquitin-protein ligase RNF31
UniProt Gene Name
RNF31
UniProt Synonym Gene Names
ZIBRA; HOIP
UniProt Entry Name
RNF31_HUMAN
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Product Notes
The RNF31 rnf31 (Catalog #AAA119079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF31 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's RNF31 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the RNF31 rnf31 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNF31, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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