IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human testis tissue using AAA232141 at dilution of 1:100)
Rabbit anti-Human, Mouse RNF41 Polyclonal Antibody | anti-RNF41 antibody
RNF41 Antibody
Gene Names
RNF41; FLRF; NRDP1; SBBI03
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Antigen Affinity Purified
Synonyms
RNF41, Antibody; RNF41 Antibody; E3 ubiquitin-protein ligase NRDP1; RING finger protein 41; RNF41; FLRF; NRDP1; SBBI03; anti-RNF41 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
317
Applicable Applications for anti-RNF41 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Species
Human
Immunogen
Recombinant human E3 ubiquitin-protein ligase NRDP1 protein (1-317AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-79996 / sc-79997 / sc-98353
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human testis tissue using AAA232141 at dilution of 1:100)
IHC (Immunohistochemisry)
(Immunohistochemistry of paraffin-embedded human testis tissue using AAA232141 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human prostate cancer using AAA232141 at dilution of 1:100)
IHC (Immunohiostchemistry)
(Immunohistochemistry of paraffin-embedded human prostate cancer using AAA232141 at dilution of 1:100)
WB (Western Blot)
(Western blotAll lanes: RNF41 antibody at 5.55 ug/ml+ Mouse brain tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 36,28 kDaObserved band size: 36,50,55 kDa)
WB (Western Blot)
(Western blotAll lanes: RNF41 antibody at 5.55 ug/ml+ Mouse brain tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 36,28 kDaObserved band size: 36,50,55 kDa)
Related Product Information for anti-RNF41 antibody
Acts as E3 ubiquitin-protein ligase and regulates the degradation of target proteins. Polyubiquitinates MYD88. Negatively regulates MYD88-dependent production of proinflammatory cytokines. Can promote TRIF-dependent production of type I interferon and inhibits infection with vesicular stomatitis virus (By similarity). Promotes also activation of TBK1 and IRF3. Involved in the ubiquitination of erythropoietin (EPO) and interleukin-3 (IL-3) receptors. Thus, through maintaining basal levels of cytokine receptors, RNF41 is involved in the control of hematopoietic progenitor cell differentiation into myeloerythroid lineages (By similarity). Contributes to the maintenance of steady-state ERBB3 levels by mediating its growth factor-independent degradation. Involved in the degradation of the inhibitor of apoptosis BIRC6 and thus is an important regulator of cell death by promoting apoptosis. Acts also as a PARK2 modifier that accelerates its degradation, resulting in a reduction of PARK2 activity, influencing the balance of intracellular redox state. The RNF41-PARK2 pathway regulates autophagosome-lysosome fusion during late mitophagy. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control (PubMed:24949970).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,965 Da
NCBI Official Full Name
E3 ubiquitin-protein ligase NRDP1 isoform 1
NCBI Official Synonym Full Names
ring finger protein 41
NCBI Official Symbol
RNF41
NCBI Official Synonym Symbols
FLRF; NRDP1; SBBI03
NCBI Protein Information
E3 ubiquitin-protein ligase NRDP1
UniProt Protein Name
E3 ubiquitin-protein ligase NRDP1
UniProt Gene Name
RNF41
UniProt Synonym Gene Names
FLRF; NRDP1
UniProt Entry Name
RNF41_HUMAN
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Product Notes
The RNF41 rnf41 (Catalog #AAA232141) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The RNF41 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's RNF41 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the RNF41 rnf41 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RNF41, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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