IF (Immunofluorescence)
(Immunofluorescence of SCF in Human Brain tissue with SCF antibody at 20 μg/mL.)
Rabbit SCF Polyclonal Antibody | anti-KITLG antibody
SCF Antibody
Gene Names
KITLG; SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
SCF Antibody is affinity chromatography purified via peptide column.
Synonyms
SCF, Antibody; SCF Antibody; SCF; SF; MGF; FPH2; KL-1; Kitl; SHEP7; Kit ligand; Mast cell growth factor; KIT ligand; anti-KITLG antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
SCF Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
273
Applicable Applications for anti-KITLG antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
SCF antibody was raised against an 18 amino acid synthetic peptide from near the center of human SCF.
Buffer
SCF Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
Antibody can be stored at 4 degree C up to one year. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of SCF in Human Brain tissue with SCF antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of SCF in Human Brain tissue with SCF antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SCF in mouse brain tissue with SCF antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SCF in mouse brain tissue with SCF antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of SCF in A431 cell lysate with SCF antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of SCF in A431 cell lysate with SCF antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-KITLG antibody
SCF Antibody: Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
Predicted: 30 kDa
Observed: 45 kDa
Observed: 45 kDa
NCBI Official Full Name
Kit ligand
NCBI Official Synonym Full Names
KIT ligand
NCBI Official Symbol
KITLG
NCBI Official Synonym Symbols
SF; MGF; SCF; FPH2; KL-1; Kitl; SHEP7
NCBI Protein Information
kit ligand; c-Kit ligand; steel factor; stem cell factor; mast cell growth factor; familial progressive hyperpigmentation 2
UniProt Protein Name
Kit ligand
UniProt Gene Name
KITLG
UniProt Synonym Gene Names
MGF; SCF; MGF; SCF; sKITLG
UniProt Entry Name
SCF_HUMAN
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Product Notes
The KITLG kitlg (Catalog #AAA40133) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SCF Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SCF can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the KITLG kitlg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SCF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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