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product-image-AAA45397_IHC11.jpg IHC (Immunohistochemisry) (Anti-SDHC antibody, AAA45397, IHC(P)IHC(P): Human Gastric Cancer Tissue)

Rabbit SDHC Polyclonal Antibody | anti-SDHC antibody

Anti-SDHC antibody

Gene Names
SDHC; CYBL; PGL3; QPS1; SDH3; CYB560
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
SDHC, Antibody; Anti-SDHC antibody; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa; CYB560 antibody; C560_HUMAN antibody; CYBL antibody; Cytochrome B large subunit of complex II antibody; Integral membrane protein CII-3 antibody; mitochondrial antibody; PGL3 antibody; QPs-1 antibody; QPs1 antibody; SDH3 antibody; sdhC antibody; Succinate dehydrogenase complex subunit C antibody; Succinate dehydrogenase complex subunit C integral membrane protein 15kDa antibody; Succinate dehydrogenase cytochrome b560 subunit antibody; Succinate dehydrogenase cytochrome b560 subunit mitochondrial antibody; Succinate dehydrogenase cytochrome b560 subunit, mitochondrial precursor antibody; Succinate-ubiquinone oxidoreductase cytochrome B large subunit antibody; anti-SDHC antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
169
Applicable Applications for anti-SDHC antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the N-terminus of human SDHC (35-50aa KEEMERFWNKNIGSNR), different from the related mouse and rat sequences by three amino acids.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.

IHC (Immunohistochemisry)

(Anti-SDHC antibody, AAA45397, IHC(P)IHC(P): Human Gastric Cancer Tissue)

product-image-AAA45397_IHC11.jpg IHC (Immunohistochemisry) (Anti-SDHC antibody, AAA45397, IHC(P)IHC(P): Human Gastric Cancer Tissue)

IHC (Immunohiostchemistry)

(Anti-SDHC antibody, AAA45397, IHC(P)IHC(P): Rat Gaster Tissue)

product-image-AAA45397_IHC13.jpg IHC (Immunohiostchemistry) (Anti-SDHC antibody, AAA45397, IHC(P)IHC(P): Rat Gaster Tissue)

WB (Western Blot)

(Anti-SDHC antibody, AAA45397, Western blottingAll lanes: Anti SDHC (AAA45397) at 0.5ug/mlLane 1: Rat Liver Tissue Lysate at 50ugLane 2: Mouse Liver Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 19KDObserved bind size: 19KD)

product-image-AAA45397_WB15.jpg WB (Western Blot) (Anti-SDHC antibody, AAA45397, Western blottingAll lanes: Anti SDHC (AAA45397) at 0.5ug/mlLane 1: Rat Liver Tissue Lysate at 50ugLane 2: Mouse Liver Tissue Lysate at 50ugLane 3: HELA Whole Cell Lysate at 40ugPredicted bind size: 19KDObserved bind size: 19KD)
Related Product Information for anti-SDHC antibody
Description: Rabbit IgG polyclonal antibody for Succinate dehydrogenase cytochrome b560 subunit, mitochondrial(SDHC) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: SDHC(succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa) also known as SDH3, SUCCINATE DEHYDROGENASE CYTOCHROME b. The SDHC gene contains 6 exons. Oostveen et al.(1995) found that in fact it was protein from the bovine SDH3 gene(encoding 1 of the 2 integral membrane proteins) that complemented the hamster mutation. The authors localized the human SDH3 gene to the short arm of chromosome one, within 1 to 2 Mb from the centromere. Additionally, the authors stated that Southern analyses of human genomic DNA suggested that there are multiple SDH3 genes or pseudogenes. Elbehti-Green et al.(1998) confirmed the assignment of the SDHC gene to 1q21 by FISH. Baysal et al.(2004) described a family with PGL3 in which an 8,372-bp deletion in the SDHC gene was transmitted both maternally and paternally, without evidence of genomic imprinting. 

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
12,474 Da
NCBI Official Full Name
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
NCBI Official Synonym Full Names
succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
NCBI Official Symbol
SDHC
NCBI Official Synonym Symbols
CYBL; PGL3; QPS1; SDH3; CYB560
NCBI Protein Information
succinate dehydrogenase cytochrome b560 subunit, mitochondrial; integral membrane protein CII-3b; succinate dehydrgenase cytochrome b; cytochrome B large subunit of complex II; succinate dehydrogenase 3, integral membrane subunit; succinate-ubiquinone oxidoreductase cytochrome B large subunit; succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD
UniProt Protein Name
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial
UniProt Gene Name
SDHC
UniProt Synonym Gene Names
CYB560; SDH3; QPs1; CYBL
UniProt Entry Name
C560_HUMAN

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Product Notes

The SDHC sdhc (Catalog #AAA45397) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SDHC antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SDHC can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SDHC sdhc for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SDHC, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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