IF (Immunofluorescence)
(Immunofluorescence of SELK in human heart tissue with SELK antibody at 20 μg/mL.)
Rabbit SELK Polyclonal Antibody | anti-SELK antibody
SELK Antibody
Gene Names
SELK; SelK; HSPC030; HSPC297
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Western Blot, ELISA
Purity
SELK Antibody is affinity chromatography purified via peptide column.
Synonyms
SELK, Antibody; SELK Antibody; SELK; SelK; HSPC030; HSPC297; Selenoprotein K; selenoprotein K; anti-SELK antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
SELK Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
94
Applicable Applications for anti-SELK antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
SELK antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human SELK.
Buffer
SELK Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SELK antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of SELK in human heart tissue with SELK antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of SELK in human heart tissue with SELK antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of SELK in A20 cell lysate with SELK antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of SELK in A20 cell lysate with SELK antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-SELK antibody
SELK Antibody: SELK is a selenoprotein, containing a selenocysteine residue at its active site. SELK is localized to the endoplasmic reticulum and is highly expressed in the heart, where it may function as an antioxidant. SELK can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex, suggesting that SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins. SELK is also thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages. When these macrophages are activated through different Toll-like receptors, this cleavage is inhibited
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
10 kDa
NCBI Official Full Name
selenoprotein K
NCBI Official Symbol
SELK
NCBI Official Synonym Symbols
SelK; HSPC030; HSPC297
NCBI Protein Information
selenoprotein K
UniProt Protein Name
Selenoprotein K
UniProt Gene Name
SELK
UniProt Synonym Gene Names
SelK
UniProt Entry Name
SELK_HUMAN
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Product Notes
The SELK selk (Catalog #AAA40116) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SELK Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SELK can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SELK selk for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SELK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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