IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 antibody.)
Rabbit anti-Human, Mouse SENP3 Polyclonal Antibody | anti-SENP3 antibody
SENP3 Antibody
Gene Names
SENP3; SSP3; Ulp1; SMT3IP1
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
SENP3, Antibody; SENP3 Antibody; Sentrin-specific protease 3; EC=3.4.22.-; Sentrin/SUMO-specific protease SENP3; SUMO-1-specific protease 3; SSP3; anti-SENP3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total SENP3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
574
Applicable Applications for anti-SENP3 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from Internal of human SENP3.
Target Name
SENP3
Preparation and Storage
Store at -20 degree C
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 antibody.)
IHC (Immunohiostchemistry)
(Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using SENP3 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using SENP3 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from Jurkat cells, using SENP3 antibody.)
Related Product Information for anti-SENP3 antibody
Protease that releases SUMO2 and SUMO3 monomers from sumoylated substrates, but has only weak activity against SUMO1 conjugates. Deconjugates SUMO2 from MEF2D, which increases its transcriptional activation capability. Deconjugates SUMO2 and SUMO3 from CDCA8. Redox sensor that, when redistributed into nucleoplasm, can act as an effector to enhance HIF1A transcriptional activity by desumoylating EP300. Required for rRNA processing through deconjugation of SUMO2 and SUMO3 from nucleophosmin, NPM1. Plays a role in the regulation of sumoylation status of ZNF148. Functions as a component of the Five Friends of Methylated CHTOP (5FMC) complex; the 5FMC complex is recruited to ZNF148 by methylated CHTOP, leading to desumoylation of ZNF148 and subsequent transactivation of ZNF148 target genes.Yeh E.T.H., Gene 248:1-14(2000).Choi S.J., Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.Wiemann S., Genome Res. 11:422-435(2001).
Product Categories/Family for anti-SENP3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
65,010 Da
NCBI Official Full Name
sentrin-specific protease 3
NCBI Official Synonym Full Names
SUMO1/sentrin/SMT3 specific peptidase 3
NCBI Official Symbol
SENP3
NCBI Official Synonym Symbols
SSP3; Ulp1; SMT3IP1
NCBI Protein Information
sentrin-specific protease 3
UniProt Protein Name
Sentrin-specific protease 3
UniProt Gene Name
SENP3
UniProt Synonym Gene Names
SSP3; SUSP3
UniProt Entry Name
SENP3_HUMAN
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Product Notes
The SENP3 senp3 (Catalog #AAA306916) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SENP3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SENP3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SENP3 senp3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SENP3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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