IHC (Immunohiostchemistry)
(SFRP4 was detected in paraffin-embedded sections of human endometrial carcinoma tissues using rabbit anti SFRP4 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method.)
anti-Human SFRP4 Polyclonal Antibody | anti-SFRP4 antibody
Anti-SFRP4 Antibody
Gene Names
SFRP4; FRP-4; FRPHE; sFRP-4
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Immunogen Affinity Purified
Synonyms
SFRP4, Antibody; Anti-SFRP4 Antibody; Secreted frizzled-related protein 4; Frizzled protein; Frizzled protein human endometrium; FRP 4; FRP4; FrpHE; human endometrium; sFRP-4; Sfrp4; SFRP4_HUMAN; secreted frizzled-related protein 4; anti-SFRP4 antibody
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Immunogen Affinity Purified
Form/Format
Lyophilized. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Sequence Length
346
Applicable Applications for anti-SFRP4 antibody
ELISA, IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
E Coli-derived human SFRP4 recombinant protein (Position: A22-K303). Human SFRP4 shares 96.8% and 96.1% amino acid (aa) sequence identity with mouse and rat SFRP4, respectively.
Ig Type
Rabbit IgG
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquoted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(SFRP4 was detected in paraffin-embedded sections of human endometrial carcinoma tissues using rabbit anti SFRP4 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method.)
IHC (Immunohiostchemistry)
(SFRP4 was detected in paraffin-embedded sections of human endometrial carcinoma tissues using rabbit anti SFRP4 Antigen Affinity purified polyclonal antibody at 1ug/mL. The immunohistochemical section was developed using SABC method.)
WB (Western Blot)
(Western blot analysis of SFRP4 expression in A549 whole cell lysates (lane 1) and SW620 whole cell lysates (lane 2). SFRP4 at 49KD was detected using rabbit anti- SFRP4 Antigen Affinity purified polyclonal antibody at0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method.)
WB (Western Blot)
(Western blot analysis of SFRP4 expression in A549 whole cell lysates (lane 1) and SW620 whole cell lysates (lane 2). SFRP4 at 49KD was detected using rabbit anti- SFRP4 Antigen Affinity purified polyclonal antibody at0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method.)
Related Product Information for anti-SFRP4 antibody
Description: Rabbit IgG polyclonal antibody for Secreted frizzled-related protein 4(SFRP4) detection. Tested with WB, IHC-P, ELISA in Human.
Background: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. It is mapped to 7p14.1. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, and reduces glucose-induced insulin secretion through decreased beta-cell exocytosis.
Background: Secreted frizzled-related protein 4 (SFRP4) is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. It is mapped to 7p14.1. The expression of SFRP4 in ventricular myocardium correlates with apoptosis related gene expression. And SFRP4 is a hub gene in a Type 2 Diabetes-associated gene coexpression module in human islets, and reduces glucose-induced insulin secretion through decreased beta-cell exocytosis.
References
1. "Entrez Gene: SFRP4 secreted frizzled-related protein 4". 2. Horvath LG, Lelliott JE, Kench JG et al. (2007). "Secreted frizzled-related protein 4 inhibits proliferation and metastatic potential in prostate cancer.". Prostate 67 (10): 1081-90.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,827 Da
NCBI Official Full Name
secreted frizzled-related protein 4
NCBI Official Synonym Full Names
secreted frizzled related protein 4
NCBI Official Symbol
SFRP4
NCBI Official Synonym Symbols
FRP-4; FRPHE; sFRP-4
NCBI Protein Information
secreted frizzled-related protein 4
UniProt Protein Name
Secreted frizzled-related protein 4
UniProt Gene Name
SFRP4
UniProt Synonym Gene Names
FRPHE; sFRP-4; FrpHE
UniProt Entry Name
SFRP4_HUMAN
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Product Notes
The SFRP4 sfrp4 (Catalog #AAA46479) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-SFRP4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SFRP4 can be used in a range of immunoassay formats including, but not limited to, ELISA, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SFRP4 sfrp4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SFRP4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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