IHC (Immunohiostchemistry)
(Immunochemical staining of human SH3GLB2 in human rectum with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Rabbit anti-Human SH3GLB2 Polyclonal Antibody | anti-SH3GLB2 antibody
Anti-SH3GLB2 Antibody, Rabbit Polyclonal
Reactivity
Human
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
SH3GLB2, Antibody; Anti-SH3GLB2 Antibody, Rabbit Polyclonal; SH3GLB2 Antibody, Rabbit PAb, Antigen Affinity Purified; SH3-domain GRB2-like endophilin B2; Anti-PP6569 Antibody; Anti-PP9455 Antibody; Anti-RP11-167N5.3 Antibody; Anti-RRIG1 Antibody; anti-SH3GLB2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human SH3GLB2
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; PBS, pH7.0 with 0.03% Proclin300
Applicable Applications for anti-SH3GLB2 antibody
IHC (Immunohistochemistry)
Immunogen
E Coli-derived Human SH3GLB2 fragment
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with E Coli-derived Human SH3GLB2 fragment, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Avoid repeated freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Immunochemical staining of human SH3GLB2 in human rectum with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohiostchemistry)
(Immunochemical staining of human SH3GLB2 in human rectum with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human SH3GLB2 in human urinary bladder with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
IHC (Immunohistochemistry)
(Immunochemical staining of human SH3GLB2 in human urinary bladder with rabbit polyclonal antibody at 1:100 dilution, formalin-fixed paraffin embedded sections.)
Related Product Information for anti-SH3GLB2 antibody
SH3GLB2 (SH3 Domain Containing GRB2 Like, Endophilin B2) is a Protein Coding gene. The SH3GLB2 gene, located on 9q34.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, chicken, zebrafish, C.elegans, and frog. An important paralog of this gene is SH3GLB1. SH3GLB2 is widely expressed in skin, prostate, and other tissues. Endophilin B2 (SH3GLB2) positively regulates the endocytic pathway in response to growth factor signaling, autophagy induction, and viral entry. In humans, the Spas-1 ortholog SH3GLB2 has been reported to be overexpressed in prostate cancer metastases. The related pathway of SH3GLB2 is Endocytosis. 221 organisms have orthologs with the human gene SH3GLB2.
References
Serfass JM, et al. (2017) Endophilin b2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza a virus infection. J Biol Chem 292 (24): 10097-10111.Pierrat B, et al. (2001) Sh3glb, a new endophilin-related protein family featuring an sh3 domain. Genomics 71 (2): 222-234.Fasso M, et al. (2008) Spas-1 (stimulator of prostatic adenocarcinoma-specific t cells)/sh3glb2: A prostate tumor antigen identified by ctla-4 blockade. Proc Natl Acad Sci U S A 105 (9): 3509-3514.
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Product Notes
The SH3GLB2 (Catalog #AAA256253) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-SH3GLB2 Antibody, Rabbit Polyclonal reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SH3GLB2 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SH3GLB2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3GLB2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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