WB (Western Blot)
(Detection of human SBDS by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SBDS antibody AAA213060 (lot AAA213060-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
Rabbit anti-Human Shwachman-Bodian-Diamond Syndrome/SBDS Polyclonal Antibody | anti-SBDS antibody
Rabbit anti-Shwachman-Bodian-Diamond Syndrome/SBDS Antibody, Affinity Purified
Gene Names
SBDS; SDS; SWDS; CGI-97
Reactivity
Human
Applications
Immunoprecipitation, Western Blot
Purity
Antigen Affinity Purified
Synonyms
Shwachman-Bodian-Diamond Syndrome/SBDS, Antibody; Rabbit anti-Shwachman-Bodian-Diamond Syndrome/SBDS Antibody, Affinity Purified; Shwachman-Bodian-Diamond syndrome protein; ribosome maturation protein SBDS; SWDS; SBDS, ribosome assembly guanine nucleotide exchange factor; CGI-97; SDS; Ribosome maturation protein SBDS; SBDS, ribosome maturation factor; anti-SBDS antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid. Whole IgG. Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide
Concentration
1000ug/ml (varies by lot)
Applicable Applications for anti-SBDS antibody
IP (Immunoprecipitation), WB (Western Blot)
Predicted Reactivity
Bovine, Orangutan
Immunogen
Between 200 and C-terminus
Conjugation
Unconjugated
Preparation and Storage
Store at 2-8 degree C
Shelf Life: 1 year from date of receipt
Shelf Life: 1 year from date of receipt
WB (Western Blot)
(Detection of human SBDS by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SBDS antibody AAA213060 (lot AAA213060-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
WB (Western Blot)
(Detection of human SBDS by western blot. Samples: Whole cell lysate (50 ug) from HeLa, HEK293T, and Jurkat cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SBDS antibody AAA213060 (lot AAA213060-1) used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
IP (Immunoprecipitation)
(Detection of human SBDS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SBDS antibody AAA213060 (lot AAA213060-1) used for IP at 6 ug per reaction. SBDS was also immunoprecipitated by rabbit anti-SBDS antibody BL19876. For blotting immunoprecipitated SBDS, AAA213060 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
IP (Immunoprecipitation)
(Detection of human SBDS by western blot of immunoprecipitates. Samples: Whole cell lysate (0.5 or 1.0 mg per IP reaction; 20% of IP loaded) from 293T cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SBDS antibody AAA213060 (lot AAA213060-1) used for IP at 6 ug per reaction. SBDS was also immunoprecipitated by rabbit anti-SBDS antibody BL19876. For blotting immunoprecipitated SBDS, AAA213060 was used at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.)
Related Product Information for anti-SBDS antibody
Shwachman-Bodian-Diamond Syndrome/SBDS is required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFTUD1, it triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. SBDS is required for normal levels of protein synthesis. It may play a role in cellular stress resistance and cellular response to DNA damage. It may also play a role in cell proliferation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y3A5].
Product Categories/Family for anti-SBDS antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
28,764 Da
NCBI Official Full Name
ribosome maturation protein SBDS
NCBI Official Synonym Full Names
Shwachman-Bodian-Diamond syndrome
NCBI Official Symbol
SBDS
NCBI Official Synonym Symbols
SDS; SWDS; CGI-97
NCBI Protein Information
ribosome maturation protein SBDS
UniProt Protein Name
Ribosome maturation protein SBDS
UniProt Gene Name
SBDS
UniProt Entry Name
SBDS_HUMAN
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Product Notes
The SBDS sbds (Catalog #AAA213060) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-Shwachman-Bodian-Diamond Syndrome/SBDS Antibody, Affinity Purified reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Shwachman-Bodian-Diamond Syndrome/SBDS can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), WB (Western Blot). Researchers should empirically determine the suitability of the SBDS sbds for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Shwachman-Bodian-Diamond Syndrome/SBDS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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