IF (Immunofluorescence)
(Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 μg/mL.)
Rabbit anti-Human SIPA1 Polyclonal Antibody | anti-SIPA1 antibody
SIPA1 Antibody
Gene Names
SIPA1; SPA1
Reactivity
Human
Applications
Immunofluorescence, Western Blot, ELISA
Purity
SIPA1 Antibody is affinity chromatography purified via peptide column.
Synonyms
SIPA1, Antibody; SIPA1 Antibody; SIPA1; SPA1; Signal-induced proliferation-associated protein 1; GTPase-activating protein Spa-1; Sipa-1; signal-induced proliferation-associated 1; anti-SIPA1 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Specificity
At least three isoforms of SIPA1 are known to exist; this antibody will recognize all three isoforms. This antibody is specific for SIPA1 and will not recognize the other SIPA1 family of proteins.
Purity/Purification
SIPA1 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
1042
Applicable Applications for anti-SIPA1 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
SIPA1 antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human SIPA1.
Buffer
SIPA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SIPA1 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of SIPA1 in human brain cells with SIPA1 antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of SIPA1 in human brain tissue lysate with SIPA1 antibody at 1 μg/mL.)
Related Product Information for anti-SIPA1 antibody
SIPA1 Antibody: Signal-induced proliferation 1 (SIPA1) is a member of the SIPA1 family of RapGAPs, a family of mitogen-induced GTPase activating proteins. SIPA1 exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. When abnormally or prematurely expressed, SIPA1 may also hamper mitogen-induced cell cycle progression and may increase metastases in human cancers.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
112,149 Da
NCBI Official Full Name
signal-induced proliferation-associated protein 1
NCBI Official Synonym Full Names
signal-induced proliferation-associated 1
NCBI Official Symbol
SIPA1
NCBI Official Synonym Symbols
SPA1
NCBI Protein Information
signal-induced proliferation-associated protein 1; sipa-1; p130 SPA-1; GTPase-activating protein Spa-1; signal-induced proliferation-associated gene 1
UniProt Protein Name
Signal-induced proliferation-associated protein 1
UniProt Gene Name
SIPA1
UniProt Synonym Gene Names
SPA1; Sipa-1
UniProt Entry Name
SIPA1_HUMAN
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Product Notes
The SIPA1 sipa1 (Catalog #AAA40229) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIPA1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SIPA1 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SIPA1 sipa1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIPA1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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