IF (Immunofluorescence)
(Immunofluorescence of SIVA in mouse liver cells with SIVA antibody at 20 μg/mL.)
Chicken anti-Human, Mouse SIVA Polyclonal Antibody | anti-SIVA1 antibody
SIVA Antibody
Gene Names
SIVA1; SIVA; CD27BP; Siva-1; Siva-2
Reactivity
Human, Mouse
Applications
Immunofluorescence, Western Blot, ELISA
Purity
SIVA Antibody is affinity chromatography purified via peptide column.
Synonyms
SIVA, Antibody; SIVA Antibody; SIVA; CD27BP; Siva-1; Siva-2; Apoptosis regulatory protein Siva; CD27-binding protein; SIVA1, apoptosis-inducing factor; anti-SIVA1 antibody
Host
Chicken
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgY
Purity/Purification
SIVA Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
175
Applicable Applications for anti-SIVA1 antibody
IF (Immunofluorescence), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
SIVA antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SIVA.
Buffer
SIVA Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SIVA antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of SIVA in mouse liver cells with SIVA antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of SIVA in mouse liver cells with SIVA antibody at 20 μg/mL.)
WB (Western Blot)
(Western blot analysis of SIVA in mouse liver tissue lysate with SIVA antibody at 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of SIVA in mouse liver tissue lysate with SIVA antibody at 1 μg/mL.)
Related Product Information for anti-SIVA1 antibody
SIVA Antibody: SIVA plays an important role in the apoptotic pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. SIVA is a small cysteine-rich protein with a unique N-terminal amphipathic helical region, a death domain homology region (DDHR) and a C-terminal cysteine-rich B-box-like or zinc-finger-like structure. The DDHR domain binds to CD27 and induces apoptosis in T cells through a caspase-dependent mitochondrial pathway. SIVA inhibits BCL2L1 isoform Bcl-xL anti-apoptotic activity and inhibits activation of NFκ-B and promotes T-cell receptor-mediated apoptosis. SIVA represents a potential therapeutic target for the treatment of neuronal cell death diseases.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
11,778 Da
NCBI Official Full Name
apoptosis regulatory protein Siva isoform 1
NCBI Official Synonym Full Names
SIVA1, apoptosis-inducing factor
NCBI Official Symbol
SIVA1
NCBI Official Synonym Symbols
SIVA; CD27BP; Siva-1; Siva-2
NCBI Protein Information
apoptosis regulatory protein Siva; CD27-binding (Siva) protein
UniProt Protein Name
Apoptosis regulatory protein Siva
UniProt Gene Name
SIVA1
UniProt Synonym Gene Names
SIVA; CD27BP
UniProt Entry Name
SIVA_HUMAN
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Product Notes
The SIVA1 siva1 (Catalog #AAA39462) is an Antibody produced from Chicken and is intended for research purposes only. The product is available for immediate purchase. The SIVA Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SIVA can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SIVA1 siva1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIVA, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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