IHC (Immunohiostchemistry)
(SLC15A3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC15A3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit SLC15A3 Polyclonal Antibody | anti-SLC15A3 antibody
SLC15A3 Antibody (Center)
Gene Names
SLC15A3; OCTP; PHT2; PTR3
Reactivity
Human (Predicted: Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
This antibody is purified through a protein A column, followed by peptide affinity purification.
Synonyms
SLC15A3, Antibody; SLC15A3 Antibody (Center); Solute carrier family 15 member 3; Osteoclast transporter; Peptide transporter 3; Peptide/histidine transporter 2; SLC15A3; OCTP; PHT2; PTR3; anti-SLC15A3 antibody
Host
Rabbit
Reactivity
Human (Predicted: Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
This SLC15A3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-197 amino acids from the Central region of human SLC15A3.
Purity/Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Sequence Length
581
Applicable Applications for anti-SLC15A3 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Function
Proton-coupled amino-acid transporter that transports free histidine and certain di- and tripeptides, and is involved in innate immune response (By similarity). Also able to transport carnosine (PubMed:31073693, PubMed:31254495). Involved in the detection of microbial pathogens by toll-like receptors (TLRs) and NOD-like receptors (NLRs), probably by mediating transport of bacterial peptidoglycans across the endolysosomal membrane: catalyzes the transport of certain bacterial peptidoglycans, such as muramyl dipeptide (MDP), the NOD2 ligand (By similarity).
Cellular Location
Lysosome membrane; Multi-pass membrane protein. Endosome membrane {ECO:0000250|UniProtKB:Q8BPX9}; Multi-pass membrane protein.
Preparation and Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(SLC15A3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC15A3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(SLC15A3 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC15A3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(Anti-SLC15A3 Antibody (Center) at 1:2000 dilution + SK-BR-3 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
WB (Western Blot)
(Anti-SLC15A3 Antibody (Center) at 1:2000 dilution + SK-BR-3 whole cell lysate Lysates/proteins at 20 ug per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 64 kDa Blocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-SLC15A3 antibody
SLC15A3 is proton oligopeptide cotransporter. Transports free histidine and certain di-and tripeptides (By similarity).
Product Categories/Family for anti-SLC15A3 antibody
References
Daniel, H., et al. Pflugers Arch. 447(5):610-618(2004) Sakata, K., et al. Biochem. J. 356 (PT 1), 53-60 (2001) : Botka, C.W., et al. AAPS PharmSci 2 (2), E16 (2000) :
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
63560
NCBI Official Full Name
solute carrier family 15 member 3
NCBI Official Synonym Full Names
solute carrier family 15 (oligopeptide transporter), member 3
NCBI Official Symbol
SLC15A3
NCBI Official Synonym Symbols
OCTP; PHT2; PTR3
NCBI Protein Information
solute carrier family 15 member 3
UniProt Protein Name
Solute carrier family 15 member 3
UniProt Gene Name
SLC15A3
UniProt Synonym Gene Names
OCTP; PHT2; PTR3
UniProt Entry Name
S15A3_HUMAN
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Product Notes
The SLC15A3 slc15a3 (Catalog #AAA286608) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC15A3 Antibody (Center) reacts with Human (Predicted: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's SLC15A3 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the SLC15A3 slc15a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC15A3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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