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FCM/FACS (Flow Cytometry)
(SLC25A6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Rabbit anti-Human SLC25A6 Polyclonal Antibody | anti-SLC25A6 antibody
SLC25A6 Antibody (Center)
Gene Names
SLC25A6; 2; 3; ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y
Reactivity
Human
Applications
Flow Cytometry, Functional Assay, Immunofluorescence, Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SLC25A6, Antibody; SLC25A6 Antibody (Center); ADP/ATP translocase 3; ADP,ATP carrier protein 3; ADP,ATP carrier protein; isoform T2; ANT 2; Adenine nucleotide translocator 3; ANT 3; Solute carrier family 25 member 6; N-terminally processed; SLC25A6; ANT3; anti-SLC25A6 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SLC25A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the Central region of human SLC25A6.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.44 (varies by lot)
Sequence Positions
128-155
Sequence Length
298
Applicable Applications for anti-SLC25A6 antibody
FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Clone Names
RB32242
Function
Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. May participate in the formation of the permeability transition pore complex (PTPC) responsible for the release of mitochondrial products that triggers apoptosis.
Cellular Location
Mitochondrion inner membrane; Multi-pass membrane protein. Note=The complex formed with ARL2BP, ARL2 and SLC25A6 is expressed in mitochondria.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 2 weeks. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
FCM/FACS (Flow Cytometry)
(SLC25A6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
FCM/FACS (Flow Cytometry)
(SLC25A6 Antibody (Center) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of SLC25A6 Antibody (Center) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
IF (Immunofluorescence)
(Confocal immunofluorescent analysis of SLC25A6 Antibody (Center) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).)
IHC (Immunohiostchemistry)
(SLC25A6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC25A6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(SLC25A6 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC25A6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(SLC25A6 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SLC25A6 antibody detected the SLC25A6 protein (arrow).)
WB (Western Blot)
(SLC25A6 Antibody (Center) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SLC25A6 antibody detected the SLC25A6 protein (arrow).)
Related Product Information for anti-SLC25A6 antibody
This gene is a member of the mitochondrial carrier
subfamily of solute carrier protein genes. The product of this gene
functions as a gated pore that translocates ADP from the
mitochondrial matrix into the cytoplasm. The protein is implicated
in the function of the permability transition pore complex (PTPC),
which regulates the release of mitochondrial products that induce
apoptosis. The human genome contains several non-transcribed
pseudogenes of this gene.
subfamily of solute carrier protein genes. The product of this gene
functions as a gated pore that translocates ADP from the
mitochondrial matrix into the cytoplasm. The protein is implicated
in the function of the permability transition pore complex (PTPC),
which regulates the release of mitochondrial products that induce
apoptosis. The human genome contains several non-transcribed
pseudogenes of this gene.
Product Categories/Family for anti-SLC25A6 antibody
References
Danishuddin, M., et al. J Mol Model 16(3):535-541(2010)
Hu, Z., et al. FEBS Lett. 583(2):383-388(2009)
Yang, Z., et al. Mol. Biol. Cell 18(11):4681-4689(2007)
Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)
Jang, J.Y., et al. Cell. Immunol. 241(1):14-25(2006)
Hu, Z., et al. FEBS Lett. 583(2):383-388(2009)
Yang, Z., et al. Mol. Biol. Cell 18(11):4681-4689(2007)
Tu, L.C., et al. Mol. Cell Proteomics 6(4):575-588(2007)
Jang, J.Y., et al. Cell. Immunol. 241(1):14-25(2006)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32866
NCBI Official Full Name
ADP/ATP translocase 3
NCBI Official Synonym Full Names
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
NCBI Official Symbol
SLC25A6
NCBI Official Synonym Symbols
2; 3; ANT; AAC3; ANT3; ANT 2; ANT 3; ANT3Y
NCBI Protein Information
ADP/ATP translocase 3
UniProt Protein Name
ADP/ATP translocase 3
UniProt Gene Name
SLC25A6
UniProt Synonym Gene Names
ANT3; ANT 2; ANT 3
UniProt Entry Name
ADT3_HUMAN
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Product Notes
The SLC25A6 slc25a6 (Catalog #AAA289349) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 128-155. The SLC25A6 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC25A6 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), IF (Immunofluorescence), IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the SLC25A6 slc25a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC25A6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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