anti-Human SLC27A2 Polyclonal Antibody | anti-SLC27A2 antibody
SLC27A2 Polyclonal Antibody (Human)
Reactivity
Human
Applications
Immunocytochemistry, Western Blot
Purity
Protein A
Synonyms
SLC27A2, Antibody; SLC27A2 Polyclonal Antibody (Human); Long-chain fatty acid transport protein 2; anti-SLC27A2 antibody
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Protein A
Form/Format
PBS w/ 0.09% sodium azide
Concentration
1mg/ml (varies by lot)
Sequence
620aa
Applicable Applications for anti-SLC27A2 antibody
ICC (Immunocytochemistry), WB (Western Blot)
Immunogen
Recombinant Human SLC27A2 aa481-620
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-SLC27A2 antibody
Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes, playing an important role in hepatic fatty acid uptake (PubMed:20530735, PubMed:22022213, PubMed:24269233, PubMed:10198260, PubMed:10749848, PubMed:11980911). Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake (PubMed:20530735, PubMed:22022213, PubMed:24269233, PubMed:10198260, PubMed:10749848, PubMed:11980911).Plays a pivotal role in regulating available LCFA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis (PubMed:20530735).Can also activate branched-chain fatty acids such as phytanic acid and pristanic acid (PubMed:10198260).May contribute to the synthesis of sphingosine-1-phosphate (PubMed:24269233).Does not activate C24 bile acids, cholate and chenodeoxycholate (PubMed:11980911).In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol (PubMed:11980911).However, it is not critical for THCA activation and bile synthesis in vivo (PubMed:20530735).
NCBI and Uniprot Product Information
NCBI GeneID
Molecular Weight
70kDa
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Product Notes
The SLC27A2 (Catalog #AAA201886) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The SLC27A2 Polyclonal Antibody (Human) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLC27A2 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the SLC27A2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: 620aa. It is sometimes possible for the material contained within the vial of "SLC27A2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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