Rabbit SLC29A3 Polyclonal Antibody | anti-SLC29A3 antibody

SLC29A3 Antibody

Cat. Num. AAA40654

• Gene Names: SLC29A3; ENT3; HJCD; PHID; HCLAP
• Reactivity: Human, Mouse, Rat
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: SLC29A3 antibody is affinity chromatography purified via peptide column.
• Synonyms: SLC29A3, Antibody; SLC29A3 Antibody; Solute carrier family 29 member 3; Equilibrative nucleoside transporter 3; ENT3; HCLAP; HJCD; PHID; solute carrier family 29 (equilibrative nucleoside transporter), member 3; anti-SLC29A3 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: SLC29A3 antibody is human, mouse and rat reactive. At least two isoforms of SLC29A3 are known to exist; this antibody will detect both isoforms. SLC29A3 antibody is predicted to not cross-react with other SLC29 proteins.
• Purity/Purification: SLC29A3 antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 475

• Applicable Applications for anti-SLC29A3 antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: SLC29A3 antibody was raised against a 19 amino acid peptide near the amino terminus of human SLC29A3.; The immunogen is located within the first 50 amino acids of SLC29A3.
• Homology: Predicted species rectivity based on immunogen sequence: Bovine (95%)
• Preparation and Storage: SLC29A3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year.

IF (Immunofluorescence)

(Immunofluorescence of SLC29A3 in rat colon muscle tissue with SLC29A3 antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of SLC29A3 in rat colon tissue with SLC29A3 antibody at 5 μg/mL.)

WB (Western Blot)

(SLC29A3 Antibody.)

Related Product Information for anti-SLC29A3 antibody

SLC29A3 is a member of the equilibrative nucleoside transporter family which plays a key role in nucleoside and nucleobase uptake for salvage pathways of nucleotide synthesis (1,2). SLC29A3 is a transmembrane glycoprotein that localizes to the lysosomal membrane and is a broad selectivity, low affinity nucleoside transporter (3). Mutations in the SLC29A3 gene have been associated with H syndrome, which is characterized by cutaneous hyperpigmentation and hypertrichosis, hepatosplenomegaly, heart anomalies, and hypogonadism (4). A related disorder, PHID (pigmented hypertrichosis with insulin-dependent diabetes mellitus), has also been associated with mutations at this locus (5).

NCBI and Uniprot Product Information

• NCBI GI #: 148596922
• NCBI GeneID: 55315
• NCBI Accession #: NP_060814
• NCBI GenBank Nucleotide #: NM_018344.5
• UniProt Accession #: Q9BZD2; Q0VAM9; Q5T465; Q7RTT8; Q8IVZ0; Q9BWI2; Q9NUS9; B2RB50; B4E2Z9; B7ZA37
• Molecular Weight: Predicted: 52 kDa; ; Observed: 51 kDa
• NCBI Official Full Name: equilibrative nucleoside transporter 3 isoform a
• NCBI Official Synonym Full Names: solute carrier family 29 (equilibrative nucleoside transporter), member 3
• NCBI Official Symbol: SLC29A3
• NCBI Official Synonym Symbols: ENT3; HJCD; PHID; HCLAP
• NCBI Protein Information: equilibrative nucleoside transporter 3; solute carrier family 29 (nucleoside transporters), member 3
• UniProt Protein Name: Equilibrative nucleoside transporter 3
• UniProt Gene Name: SLC29A3
• UniProt Synonym Gene Names: ENT3; hENT3
• UniProt Entry Name: S29A3_HUMAN