IHC (Immunohiostchemistry)
(Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.)
Rabbit anti-Human, Mouse SLC38A4 Polyclonal Antibody | anti-SLC38A4 antibody
SLC38A4 Antibody
Gene Names
SLC38A4; ATA3; NAT3; PAAT; SNAT4
Reactivity
Human, Mouse
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column.
Synonyms
SLC38A4, Antibody; SLC38A4 Antibody; Solute carrier family 38 member 4, sodium-coupled neutral amino acid transporter 4, SNAT4, protein associated with ABC transporters, PAAT, ATA3, NAT3; anti-SLC38A4 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
SLC38A4 antibody is human and mouse reactive. SLC38A4 will not cross-react with other members of the SLC38 protein family.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid; Supplied in PBS containing 0.02% sodium azide.
Concentration
1 mg/mL (varies by lot)
Sequence Length
547
Applicable Applications for anti-SLC38A4 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen
SLC38A4 antibody was raised against an 18 amino acid peptide from near the center of human SLC38A4.
Homology
Predicted species reactivity based on immunogen sequence: Rat: (71%).
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
IHC (Immunohiostchemistry)
(Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SLC38A4 in mouse liver tissue with SLC38A4 antibody at 2.5 μg/mL.)
WB (Western Blot)
(Western blot analysis of SLC38A4 in mouse kidney tissue lysate with SLC38A4 antibody at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of SLC38A4 in mouse kidney tissue lysate with SLC38A4 antibody at (A) 1 and (B) 2 μg/ml.)
Related Product Information for anti-SLC38A4 antibody
SLC38A4 is found predominantly in liver and transports both cationic and neutral amino acids (1,2). The transport of cationic amino acids by SLC38A4 is sodium and pH independent, while the transport of neutral amino acids is sodium and pH dependent (2). Recent evidence suggests that SLC38A4 functions as a regulator of protein synthesis downstream of the hepatocyte nuclear factor 4a during liver development (3). It has also been suggested that SLC38A4 has ATPase activity and is critically involved in the maintenance of mitochondrial homeostasis and cell survival (4).
Product Categories/Family for anti-SLC38A4 antibody
References
Sugawara M, Nakanishi T, Fei YJ, et al. Structure and function of ATA3, a new subtype of amino acid transport system A, primarily expressed in the liver and skeletal system. Biochim. Biophys. Acta 2000; 1509:7-13. Hatanaka T, Huang W, Ling R, et al. Evidence for the transport of neutral as well as cationic amino acids by ATA3, a novel and liver-specific subtype of amino acid transport system A. Biochim. Biophys. Acta 2001 1510:10-7. Kondou H, Kawai M, Tachikawa K, et al. Sodium-coupled neutral amino acid transporter 4 functions as a regulator of protein synthesis during liver development. Hepatol. Res. 2013; 43:1211-23. Yang X, Yang J, Li L, et al. PAAT, a novel ATPase and trans-regulator of mitochondrial ABC transporters, is critically involved in the maintenance of mitochondrial homeostasis. FASEB J. 2014; 28:4821-34.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 60 kDa
Observed: 60 kDa
Observed: 60 kDa
NCBI Official Full Name
sodium-coupled neutral amino acid transporter 4
NCBI Official Synonym Full Names
solute carrier family 38 member 4
NCBI Official Symbol
SLC38A4
NCBI Official Synonym Symbols
ATA3; NAT3; PAAT; SNAT4
NCBI Protein Information
sodium-coupled neutral amino acid transporter 4
UniProt Protein Name
Sodium-coupled neutral amino acid transporter 4
UniProt Gene Name
SLC38A4
UniProt Synonym Gene Names
ATA3; NAT3; SNAT4
UniProt Entry Name
S38A4_HUMAN
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Product Notes
The SLC38A4 slc38a4 (Catalog #AAA40829) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC38A4 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC38A4 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SLC38A4 slc38a4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC38A4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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