Rabbit SLC43A2 Polyclonal Antibody | anti-SLC43A2 antibody

SLC43A2 Antibody (Center)

Cat. Num. AAA288333

• Gene Names: SLC43A2; LAT4
• Reactivity: Human, Mouse; Predicted: Bovine
• Applications: Flow Cytometry, Functional Assay, ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: SLC43A2, Antibody; SLC43A2 Antibody (Center); Large neutral amino acids transporter small subunit 4; L-type amino acid transporter 4; Solute carrier family 43 member 2; SLC43A2; LAT4; anti-SLC43A2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse; Predicted: Bovine
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This SLC43A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236-265 amino acids from the Central region of human SLC43A2.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Sequence Length: 569

• Applicable Applications for anti-SLC43A2 antibody: FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
• Antigen Region: 236-265
• Function: Uniporter that mediates the transport of the stereospecific L-phenylalanine, L-methionine and L-branched-chain amino acids, between the extracellular space and the cytoplasm and may control the transepithelial (re)absorption of neutral amino acid in kidney and small intestine (PubMed:30379325, PubMed:15659399). The transport activity is mediated through facilitated diffusion and is sodium ions-, chloride ions- and pH-independent (PubMed:15659399).
• Cellular Location: Cell membrane; Multi-pass membrane protein. Basolateral cell membrane {ECO:0000250|UniProtKB:Q8CGA3}. Note=Located at the basolateral membrane in the small intestine enterocytes, kidney proximal tubule, thick ascending limb and, to a minor extent, of distal convoluted tubule epithelial cells. {ECO:0000250|UniProtKB:Q8CGA3}
• Tissue Location: Detected in several tissues with higher expression in placenta, kidney and peripheral blood leukocytes (PubMed:15659399) In the kidney, is detected in epithelial cells of the distal tubule and collecting duct (PubMed:15659399). In the intestine, is expressed mainly in crypt cells of the intestinal microvilli and epithelial cells in the base of the villus (PubMed:15659399).
• Preparation and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(SLC43A2 Antibody (Center) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

WB (Western Blot)

(SLC43A2 Antibody (Center) western blot analysis in mouse lung tissue lysates (15ug/lane).This demonstrates the SLC43A2 antibody detected SLC43A2 protein (arrow).)

Product Categories/Family for anti-SLC43A2 antibody

Metabolism; Signal Transduction

NCBI and Uniprot Product Information

• NCBI GI #: 22748751
• NCBI GeneID: 124935
• NCBI Accession #: NP_689559.1
• NCBI GenBank Nucleotide #: NM_152346.2
• UniProt Accession #: Q8N370; Q5CD75; Q6IPM1; Q8NBX1; Q8NC21; Q8WZ00; B7Z6X9; C9JNU8; D3DTH9
• Molecular Weight: 62747
• NCBI Official Full Name: large neutral amino acids transporter small subunit 4 isoform 2
• NCBI Official Synonym Full Names: solute carrier family 43 (amino acid system L transporter), member 2
• NCBI Official Symbol: SLC43A2
• NCBI Official Synonym Symbols: LAT4
• NCBI Protein Information: large neutral amino acids transporter small subunit 4
• UniProt Protein Name: Large neutral amino acids transporter small subunit 4
• UniProt Gene Name: SLC43A2
• UniProt Synonym Gene Names: LAT4
• UniProt Entry Name: LAT4_HUMAN