WB (Western Blot)
(Western blot analysis of extracts from mouse brain, using SLC4A11 Antibody. Lane 1 was treated with the blocking peptide.)
Rabbit anti-Human, Mouse SLC4A11 Polyclonal Antibody | anti-SLC4A11 antibody
SLC4A11 Antibody
Gene Names
SLC4A11; BTR1; CHED; CDPD1; CHED2; NABC1; dJ794I6.2
Reactivity
Human, Mouse
Applications
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Synonyms
SLC4A11, Antibody; SLC4A11 Antibody; Bicarbonate transporter related protein 1; Bicarbonate transporter-related protein 1; BTR1; CDPD; CHED2; Corneal endothelial dystrophy 2 autosomal recessive; dJ794I6.2; FECD4; MGC126418; MGC126419; NaBC1; S4A11_HUMAN; Slc4a11; Sodium bicarbonate transporter-like protein 11; Sodium borate cotransporter 1; Sodium coupled borate cotransporter 1; Solute carrier family 4 member 11; Solute carrier family 4 sodium bicarbonate transporter like member 11; Solute carrier family 4 sodium borate transporter member 11; anti-SLC4A11 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
SLC4A11 antibody detects endogenous levels of total SLC4A11
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Form/Format
Liquid
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
875
Applicable Applications for anti-SLC4A11 antibody
ELISA, ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot)
Immunogen
A synthesized peptide
Subcellular Location
Plasma Membrane
Tissue Specificity
Widely expressed. Highly expressed in kidney, testis, salivary gland, thyroid, trachea and corneal endothelium. Not detected in retina and lymphocytes.
Conjugation
Unconjugated
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
WB (Western Blot)
(Western blot analysis of extracts from mouse brain, using SLC4A11 Antibody. Lane 1 was treated with the blocking peptide.)
WB (Western Blot)
(Western blot analysis of extracts from mouse brain, using SLC4A11 Antibody. Lane 1 was treated with the blocking peptide.)
IF (Immunofluorescence)
(AAA325159 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
IF (Immunofluorescence)
(AAA325159 staining NIH-3T3 by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25 degree C. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37 degree C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells using SLC4A11 antibody.)
WB (Western Blot)
(Western blot analysis of extracts from 3T3 cells using SLC4A11 antibody.)
Related Product Information for anti-SLC4A11 antibody
Function: Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration (By similarity). Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.
Subunit Structure: Homodimer.
Post-translational Modifications: Glycosylated.
Similarity: Belongs to the anion exchanger (TC 2.A.31) family.
Subunit Structure: Homodimer.
Post-translational Modifications: Glycosylated.
Similarity: Belongs to the anion exchanger (TC 2.A.31) family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Observed: 100 kD
Predicted: 100 kDa
Predicted: 100 kDa
NCBI Official Full Name
sodium bicarbonate transporter-like protein 11 isoform 3
NCBI Official Synonym Full Names
solute carrier family 4 member 11
NCBI Official Symbol
SLC4A11
NCBI Official Synonym Symbols
BTR1; CHED; CDPD1; CHED2; NABC1; dJ794I6.2
NCBI Protein Information
sodium bicarbonate transporter-like protein 11
UniProt Protein Name
Sodium bicarbonate transporter-like protein 11
UniProt Gene Name
SLC4A11
UniProt Synonym Gene Names
BTR1; NaBC1
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Product Notes
The SLC4A11 slc4a11 (Catalog #AAA325159) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLC4A11 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SLC4A11 can be used in a range of immunoassay formats including, but not limited to, ELISA, ICC (Immunocytochemistry), IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the SLC4A11 slc4a11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLC4A11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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