WB (Western Blot)
(Western blot of extracts from HUVEC cells, using SMO Antibody. The lane on the right is treated with the synthesized peptide.)
Rabbit SMO / Smoothened Polyclonal Antibody | anti-SMO antibody
Rabbit Polyclonal (IgG) to Human SMO / Smoothened
Gene Names
SMO; Gx; SMOH; FZD11
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Immunoaffinity Purified
Synonyms
SMO / Smoothened, Antibody; Rabbit Polyclonal (IgG) to Human SMO / Smoothened; Anti-SMO / Smoothened Antibody (aa68-117) IHC-plus; SMO; Frizzled family member 11; FZD11; Gx; Protein Gx; SMOH; Smoothened; Smoothened homolog; Human SMO; anti-SMO antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
SMO Antibody detects endogenous levels of total SMO protein.
Purity/Purification
Immunoaffinity Purified
Form/Format
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Concentration
1 mg/ml (varies by lot)
Sequence Length
787
Applicable Applications for anti-SMO antibody
ELISA, WB (Western Blot), IHC (Immunohistochemistry)
Target Species
Human
Immunogen Description
Synthetic peptide from human SMO (aa68-117).
Immunogen
SMO / Smoothened antibody was raised against synthetic peptide from human SMO (aa68-117).
Antigen Modification
aa68-117
Preparation and Storage
Store at -20 degree C for up to one year.
WB (Western Blot)
(Western blot of extracts from HUVEC cells, using SMO Antibody. The lane on the right is treated with the synthesized peptide.)
WB (Western Blot)
(Western blot of extracts from HUVEC cells, using SMO Antibody. The lane on the right is treated with the synthesized peptide.)
IHC (Immunohiostchemistry)
(Anti-SMO antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
IHC (Immunohiostchemistry)
(Anti-SMO antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-SMO antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
IHC (Immunohistochemistry)
(Anti-SMO antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Related Product Information for anti-SMO antibody
Smoothened, a Frizzled Receptor, is homologous to the Drosophila segment polarity Smo gene. It associates with the Patched protein to mediate the cellular response to the Hedgehog secreted protein signal, which controls patterning and growth during vertebrate development. Smoothened is activated in a number of human tumors and can function as an oncogene in basal-cell carcinomas.
Product Categories/Family for anti-SMO antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
86,397 Da
NCBI Official Full Name
smoothened homolog
NCBI Official Synonym Full Names
smoothened, frizzled class receptor
NCBI Official Symbol
SMO
NCBI Official Synonym Symbols
Gx; SMOH; FZD11
NCBI Protein Information
smoothened homolog; protein Gx; frizzled family member 11; seven transmembrane helix receptor; smoothened, frizzled family receptor; smoothened, seven transmembrane spanning receptor
UniProt Protein Name
Smoothened homolog
UniProt Gene Name
SMO
UniProt Synonym Gene Names
SMOH; SMO
UniProt Entry Name
SMO_HUMAN
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Product Notes
The SMO smo (Catalog #AAA51750) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal (IgG) to Human SMO / Smoothened reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SMO / Smoothened can be used in a range of immunoassay formats including, but not limited to, ELISA, WB (Western Blot), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SMO smo for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SMO / Smoothened, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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