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product-image-AAA284051_WB11.jpg WB (Western Blot) (SNF1LK Antibody (C-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the SNF1LK antibody detected the SNF1LK protein (arrow).)

Rabbit anti-Human, mouse SNF1LK Polyclonal Antibody | anti-SIK1 antibody

SNF1LK Antibody (C-term)

Gene Names
SIK1; MSK; SIK; EIEE30; SNF1LK
Reactivity
Human, mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SNF1LK, Antibody; SNF1LK Antibody (C-term); Serine/threonine-protein kinase SIK1; Salt-inducible kinase 1; SIK-1; Serine/threonine-protein kinase SNF1-like kinase 1; Serine/threonine-protein kinase SNF1LK; SIK1; SIK; SNF1LK; anti-SIK1 antibody
Ordering
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SNF1LK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 567-597 amino acids from the C-terminal region of human SNF1LK.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
567-597
Sequence Length
783
Applicable Applications for anti-SIK1 antibody
WB (Western Blot), IHC (Immunohistochemistry), ELISA
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

WB (Western Blot)

(SNF1LK Antibody (C-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the SNF1LK antibody detected the SNF1LK protein (arrow).)

product-image-AAA284051_WB11.jpg WB (Western Blot) (SNF1LK Antibody (C-term) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the SNF1LK antibody detected the SNF1LK protein (arrow).)

WB (Western Blot)

(SNF1LK Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SNF1LK antibody detected the SNF1LK protein (arrow).)

product-image-AAA284051_WB13.jpg WB (Western Blot) (SNF1LK Antibody (C-term) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the SNF1LK antibody detected the SNF1LK protein (arrow).)

IHC (Immunohistochemistry)

(Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)

product-image-AAA284051_IHC15.jpg IHC (Immunohistochemistry) (Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.)
Related Product Information for anti-SIK1 antibody
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Product Categories/Family for anti-SIK1 antibody
References
Hattori, M., et al., Nature 405(6784):311-319 (2000).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
84902
NCBI Official Full Name
serine/threonine-protein kinase SIK1
NCBI Official Synonym Full Names
salt-inducible kinase 1
NCBI Official Symbol
SIK1
NCBI Official Synonym Symbols
MSK; SIK; EIEE30; SNF1LK
NCBI Protein Information
serine/threonine-protein kinase SIK1
UniProt Protein Name
Serine/threonine-protein kinase SIK1
UniProt Gene Name
SIK1
UniProt Synonym Gene Names
SIK; SNF1LK; SIK-1; Serine/threonine-protein kinase SNF1LK
UniProt Entry Name
SIK1_HUMAN

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Product Notes

The SIK1 sik1 (Catalog #AAA284051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 567-597. The SNF1LK Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SNF1LK can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SIK1 sik1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SNF1LK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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