IF (Immunofluorescence)
(Immunofluorescence of SnoN in Mouse Lung cells with SnoN antibody at 20 μg/mL.)
Rabbit SnoN Polyclonal Antibody | anti-SKIL antibody
SnoN Antibody
Gene Names
SKIL; SNO; SnoA; SnoI; SnoN
Reactivity
Human, Mouse, Rat
Applications
Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
Purity
SnoN Antibody is affinity chromatography purified via peptide column.
Synonyms
SnoN, Antibody; SnoN Antibody; SnoN; SNO; SnoA; SnoI; Ski-like protein; Ski-related oncogene; SKI-like oncogene; anti-SKIL antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
SnoN Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Sequence Length
684
Applicable Applications for anti-SKIL antibody
IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
SnoN antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of human SnoN.
Buffer
SnoN Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
SnoN antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IF (Immunofluorescence)
(Immunofluorescence of SnoN in Mouse Lung cells with SnoN antibody at 20 μg/mL.)
IF (Immunofluorescence)
(Immunofluorescence of SnoN in Mouse Lung cells with SnoN antibody at 20 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SnoN in mouse lung tissue with SnoN antibody at 5 μg/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SnoN in mouse lung tissue with SnoN antibody at 5 μg/mL.)
WB (Western Blot)
(Western blot analysis of SnoN in A431 cell lysate with SnoN antibody at (A) 0.5 and (B) 1 μg/mL.)
WB (Western Blot)
(Western blot analysis of SnoN in A431 cell lysate with SnoN antibody at (A) 0.5 and (B) 1 μg/mL.)
Related Product Information for anti-SKIL antibody
SnoN Antibody: TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Like Ski, SnoN functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes. SnoN is located primarily in the nucleus in cancer tissues or cells, but in the cytoplasm in normal tissues or primary epithelial cells. There are at least four alternately spliced isoforms of SnoN; SnoN antibody will recognize all isoforms (SnoN, SnoN2, SnoI, and SnoA).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
74,784 Da
NCBI Official Full Name
ski-like protein isoform 1
NCBI Official Synonym Full Names
SKI-like proto-oncogene
NCBI Official Symbol
SKIL
NCBI Official Synonym Symbols
SNO; SnoA; SnoI; SnoN
NCBI Protein Information
ski-like protein; SKI-like oncogene; ski-related oncogene snoN
UniProt Protein Name
Ski-like protein
UniProt Gene Name
SKIL
UniProt Synonym Gene Names
SNO
UniProt Entry Name
SKIL_HUMAN
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Product Notes
The SKIL skil (Catalog #AAA40329) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SnoN Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SnoN can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SKIL skil for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SnoN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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