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product-image-AAA254744_IHC11.png IHC (Immunohistochemisry) (Immunochemical staining SORT1 in rat brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

Rabbit Sortilin/SORT1 Polyclonal Antibody | anti-SORT1 antibody

Anti-Sortilin/SORT1 Antibody, Rabbit Polyclonal

Gene Names
SORT1; NT3; Gp95; LDLCQ6
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry
Purity
Protein A & Antigen Affinity
Synonyms
Sortilin/SORT1, Antibody; Anti-Sortilin/SORT1 Antibody, Rabbit Polyclonal; SORT1 Antibody, Rabbit PAb, Antigen Affinity Purified; Anti-Gp95 Antibody; Anti-LDLCQ6 Antibody; Anti-NT3 Antibody; anti-SORT1 antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
Human Sortilin/SORT1
Purity/Purification
Protein A & Antigen Affinity
Form/Format
Liquid; 0.2um filtered solution in PBS
Applicable Applications for anti-SORT1 antibody
IHC (Immunohistochemistry)
Immunogen
A synthetic peptide corresponding to the center region of the Human SORT1
Conjugation
Unconjugated
Preparation
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human SORT1, and purified by antigen affinity chromatography.
Preparation and Storage
This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohistochemisry)

(Immunochemical staining SORT1 in rat brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

product-image-AAA254744_IHC11.png IHC (Immunohistochemisry) (Immunochemical staining SORT1 in rat brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

IHC (Immunohiostchemistry)

(Immunochemical staining SORT1 in mouse brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

product-image-AAA254744_IHC13.png IHC (Immunohiostchemistry) (Immunochemical staining SORT1 in mouse brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

IHC (Immunohistochemistry)

(Immunochemical staining SORT1 in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)

product-image-AAA254744_IHC15.png IHC (Immunohistochemistry) (Immunochemical staining SORT1 in human brain with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections).)
Related Product Information for anti-SORT1 antibody
SORT1 is the neuronal receptor for granulin, encoded by the progranulin gene (GRN), a major causal gene for inherited frontotemporal dementia (FTD). Even though sortilin binds and internalizes LDL by receptor-mediated endocytosis, mutations in the SORT1 gene are unlikely to cause autosomal dominant hypercholesterolemia and may only have a marginal effect on plasma LDL cholesterol levels. The SORT1 locus was originally identified by genome-wide association studies of low-density lipoprotein cholesterol (LDL-C) in adults.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
831
NCBI Official Full Name
Sortilin
NCBI Official Synonym Full Names
sortilin 1
NCBI Official Symbol
SORT1
NCBI Official Synonym Symbols
NT3; Gp95; LDLCQ6
NCBI Protein Information
sortilin; NTR3; glycoprotein 95; 100 kDa NT receptor; neurotensin receptor 3
UniProt Protein Name
Sortilin
UniProt Gene Name
SORT1
UniProt Synonym Gene Names
Gp95; NT3; NTR3
UniProt Entry Name
SORT_HUMAN

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Product Notes

The SORT1 sort1 (Catalog #AAA254744) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Sortilin/SORT1 Antibody, Rabbit Polyclonal reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Sortilin/SORT1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the SORT1 sort1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Sortilin/SORT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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