IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2a Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Rabbit anti-Human SPPL2a Polyclonal Antibody | anti-SPPL2A antibody
SPPL2a Antibody (N-term)
Gene Names
SPPL2A; IMP3; PSL2
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SPPL2a, Antibody; SPPL2a Antibody (N-term); Signal peptide peptidase-like 2A; SPP-like 2A; SPPL2a; 3423-; Intramembrane protease 3; IMP-3; Presenilin-like protein 2; SPPL2A; IMP3; PSL2; anti-SPPL2A antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SPPL2a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 108-138 amino acids from the N-terminal region of human SPPL2a.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
108-138
Sequence Length
520
Applicable Applications for anti-SPPL2A antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2a Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(Formalin-fixed and paraffin-embedded placenta tissue reacted with SPPL2a Antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
WB (Western Blot)
(The anti-SPPL2a Pab is used in Western blot to detect SPPL2a in Jurkat cell lysate.)
WB (Western Blot)
(The anti-SPPL2a Pab is used in Western blot to detect SPPL2a in Jurkat cell lysate.)
Related Product Information for anti-SPPL2A antibody
By searching sequence databases for homologs of Dictyostelium discoideum Impas, which shares homology with presenilin, followed by PCR of lymphocyte and hippocampus cDNA libraries, Grigorenko et al. (2002) cloned SPPL2a. This protein, which may act as an intramembrane protease, contains an N-terminal protease-associated (PA) domain, several transmembrane regions, a hydrophilic loop, conservative sequences around the first and second aspartate residues, and an invariant PAL motif near the C terminus.
Product Categories/Family for anti-SPPL2A antibody
References
Grigorenko, A. P., et al. Biochemistry 67: 826-834 (2002).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58143
NCBI Official Full Name
signal peptide peptidase-like 2A
NCBI Official Synonym Full Names
signal peptide peptidase like 2A
NCBI Official Symbol
SPPL2A
NCBI Official Synonym Symbols
IMP3; PSL2
NCBI Protein Information
signal peptide peptidase-like 2A
UniProt Protein Name
Signal peptide peptidase-like 2A
UniProt Gene Name
SPPL2A
UniProt Synonym Gene Names
IMP3; PSL2; SPP-like 2A; SPPL2a; IMP-3
UniProt Entry Name
SPP2A_HUMAN
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Product Notes
The SPPL2A sppl2a (Catalog #AAA284170) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 108-138. The SPPL2a Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SPPL2a can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the SPPL2A sppl2a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SPPL2a, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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