Rabbit SRAC1 Polyclonal Antibody | anti-SERAC1 antibody

SRAC1 Antibody (C-term)

Cat. Num. AAA285338

• Reactivity: Human, mouse (Predicted Reactivity: Bovine)
• Applications: Immunohistochemistry, ELISA, Western Blot
• Purity: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Synonyms: SRAC1, Antibody; SRAC1 Antibody (C-term); Protein SERAC1; Serine active site-containing protein 1; SERAC1; anti-SERAC1 antibody

• Host: Rabbit
• Reactivity: Human, mouse (Predicted Reactivity: Bovine)
• Clonality: Polyclonal
• Isotype: Rabbit Ig
• Specificity: This SRAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 552-581 amino acids from the C-terminal region of human SRAC1.
• Purity/Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
• Form/Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Sequence Positions: 552-581
• Sequence Length: 167

• Applicable Applications for anti-SERAC1 antibody: IHC (Immunohistochemistry), ELISA, WB (Western Blot)
• Function: Plays an important role in the phosphatidylglycerol remodeling that is essential for both mitochondrial function and intracellular cholesterol trafficking. May catalyze the remodeling of phosphatidylglycerol and be involved in the transacylation-acylation reaction to produce phosphatidylglycerol-36:1. May be involved in bis(monoacylglycerol)phosphate biosynthetic pathway.
• Cellular Location: Membrane; Single-pass membrane protein. Endoplasmic reticulum. Mitochondrion. Note=Localizes at the endoplasmic reticulum and at the endoplasmic reticulum-mitochondria interface.
• Tissue Location: Widely expressed, with predominant expression in fetal skeletal muscle and adult brain. In the brain, highest levels are found in the frontal and occipital cortices, cerebellum and hippocampus.
• Preparation and Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(SRAC1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SRAC1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(SRAC1 Antibody (C-term) western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SRAC1 antibody detected the SRAC1 protein (arrow).)

Product Categories/Family for anti-SERAC1 antibody

Signal Transduction

References

Rose, J. Phd, et al. Mol. Med. (2010) In press :
Mungall, A.J., et al. Nature 425(6960):805-811(2003)

NCBI and Uniprot Product Information

• NCBI GI #: 228008407
• NCBI GeneID: 84947
• NCBI Accession #: NP_116250.3
• NCBI GenBank Nucleotide #: NM_032861.3
• UniProt Accession #: Q96JX3; Q49AT1; Q5VTX3; Q6PKF3
• Molecular Weight: Calculated MW: 74147
• NCBI Official Full Name: protein SERAC1
• NCBI Official Synonym Full Names: serine active site containing 1
• NCBI Official Symbol: SERAC1
• NCBI Protein Information: protein SERAC1
• UniProt Protein Name: Protein SERAC1
• UniProt Gene Name: SERAC1
• UniProt Entry Name: SRAC1_HUMAN