IHC (Immunohiostchemistry)
(Immunohistochemistry of SRPX1 in human brain tissue with SRPX1 antibody at 5 ug/mL.)
Rabbit SRPX1 Polyclonal Antibody | anti-SRPX1 antibody
SRPX1 Antibody
Gene Names
SRPX; DRS; ETX1; SRPX1; HEL-S-83p
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
SRPX1, Antibody; SRPX1 Antibody; Sushi-repeat-containing protein X-linked, SRPX, DRS, ETX1; anti-SRPX1 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
464
Applicable Applications for anti-SRPX1 antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the amino terminus of human SRPX1.
Target Name
SRPX1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of SRPX1 in human brain tissue with SRPX1 antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of SRPX1 in human brain tissue with SRPX1 antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of SRPX1 in SK-N-SH cell lysate with SRPX1 antibody at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
WB (Western Blot)
(Western blot analysis of SRPX1 in SK-N-SH cell lysate with SRPX1 antibody at 0.25 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-SRPX1 antibody
SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.
Product Categories/Family for anti-SRPX1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,382 Da
NCBI Official Full Name
sushi repeat-containing protein SRPX isoform 1
NCBI Official Synonym Full Names
sushi-repeat containing protein, X-linked
NCBI Official Symbol
SRPX
NCBI Official Synonym Symbols
DRS; ETX1; SRPX1; HEL-S-83p
NCBI Protein Information
sushi repeat-containing protein SRPX
UniProt Protein Name
Sushi repeat-containing protein SRPX
UniProt Gene Name
SRPX
UniProt Synonym Gene Names
ETX1
UniProt Entry Name
SRPX_HUMAN
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Product Notes
The SRPX1 srpx (Catalog #AAA306430) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRPX1 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SRPX1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SRPX1 srpx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRPX1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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