Rabbit anti-Human SRRT Polyclonal Antibody | anti-SRRT antibody
SRRT Antibody
Gene Names
SRRT; ARS2; ASR2; serrate
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
SRRT, Antibody; SRRT Antibody; Arsenite-resistance protein 2; SRRT; ARS2; ASR2; anti-SRRT antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
875
Applicable Applications for anti-SRRT antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Serrate RNA effector molecule homolog protein (627-876aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-162539 / sc-162540 / sc-135083
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
Related Product Information for anti-SRRT antibody
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA); however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, necessary and sufficient to promote neural stem cell self-renewal. Does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
96,222 Da
NCBI Official Full Name
serrate RNA effector molecule homolog isoform c
NCBI Official Synonym Full Names
serrate, RNA effector molecule
NCBI Official Symbol
SRRT
NCBI Official Synonym Symbols
ARS2; ASR2; serrate
NCBI Protein Information
serrate RNA effector molecule homolog
UniProt Protein Name
Serrate RNA effector molecule homolog
UniProt Gene Name
SRRT
UniProt Synonym Gene Names
ARS2; ASR2
UniProt Entry Name
SRRT_HUMAN
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Product Notes
The SRRT srrt (Catalog #AAA119309) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SRRT Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SRRT can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SRRT srrt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SRRT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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