Rabbit STAT1 alpha Polyclonal Antibody | anti-STAT1 antibody

STAT1 alpha Antibody

Cat. Num. AAA40223

• Gene Names: STAT1; CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
• Reactivity: Human, Mouse, Rat
• Applications: Immunoprecipitation, Immunocytochemistry, Western Blot, ELISA
• Purity: STAT1 alpha Antibody is affinity chromatography purified via peptide column.
• Synonyms: STAT1 alpha, Antibody; STAT1 alpha Antibody; STAT1 alpha; CANDF7; ISGF-3; STAT91; signal transducer and activator of transcription 1, 91kDa; anti-STAT1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: No reaction to the 84 kDa STAT1a.
• Purity/Purification: STAT1 alpha Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Sequence Length: 750

• Applicable Applications for anti-STAT1 antibody: IP (Immunoprecipitation), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: STAT1 antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human STAT1 alpha. The sequences differ from the murine corresponding sequences by four amino acids.
• Buffer: STAT1 alpha Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: STAT1 alpha antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of STAT1 alpha in human colon tissue with STAT1 alpha antibody at 20 μg/mL.Green: STAT1 alpha Antibody (1021)Blue: DAPI staining)

IHC (Immunohistochemisry)

(Immunohistochemistry of STAT1alpha in human colon tissue with STAT1alpha antibody at 2.5 μg/ml.)

ICC (Immunocytochemistry)

(Immunocytochemistry of STAT1 alpha in HeLa cells with STAT1 alpha antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of STAT1 alpha in whole cell lysates from HeLa (H), Jurkat (J), A431 (A), K562 (K), and NIH3T3 (N) cells, with STAT1a antibody at 1 μg/mL.)

Related Product Information for anti-STAT1 antibody

STAT1 alpha Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-α, IFN-β, IFN-γ and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1α and the 84 kDa STAT1β which are encoded by the same gene with splicing variant.

NCBI and Uniprot Product Information

• NCBI GI #: 6274552
• NCBI GeneID: 6772
• NCBI Accession #: NP_009330
• NCBI GenBank Nucleotide #: NM_007315.3
• UniProt Accession #: P42224; Q53S88; Q53XW4; Q68D00; Q9UDL5; A8K989; B2RCA0; D2KFR8; D3DPI7
• Molecular Weight: 91 kDa
• NCBI Official Full Name: signal transducer and activator of transcription 1-alpha/beta isoform alpha
• NCBI Official Synonym Full Names: signal transducer and activator of transcription 1, 91kDa
• NCBI Official Symbol: STAT1
• NCBI Official Synonym Symbols: CANDF7; IMD31A; IMD31B; IMD31C; ISGF-3; STAT91
• NCBI Protein Information: signal transducer and activator of transcription 1-alpha/beta; transcription factor ISGF-3 components p91/p84; signal transducer and activator of transcription-1; signal transducer and activator of transcription 1, 91kD
• UniProt Protein Name: Signal transducer and activator of transcription 1-alpha/beta
• UniProt Gene Name: STAT1
• UniProt Entry Name: STAT1_HUMAN