IHC (Immunohiostchemistry)
(Anti-Stefin B antibody, AAA45690, IHC(P)IHC(P): Human Lung Cancer Tissue)
Rabbit anti-Human Stefin B Polyclonal Antibody | anti-CSTB antibody
Anti-Stefin B antibody
Gene Names
CSTB; PME; ULD; CST6; EPM1; STFB; EPM1A
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
Stefin B, Antibody; Anti-Stefin B antibody; Cystatin-B; cystatin B(stefin B); CHROW21 antibody; CPI B antibody; CPI-B antibody; CST6 antibody; CSTB antibody; Cystatin B antibody; Cystatin-B antibody; CYTB antibody; CYTB_HUMAN antibody; EPM1 antibody; EPM1A antibody; Liver thiol proteinase inhibitor antibody; PME antibody; Stefin-B antibody; STFB antibody; ULD antibody; anti-CSTB antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
98
Applicable Applications for anti-CSTB antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human Stefin B (26-45aa QLEEKENKKFPVFKAVSFKS).
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
IHC (Immunohiostchemistry)
(Anti-Stefin B antibody, AAA45690, IHC(P)IHC(P): Human Lung Cancer Tissue)
IHC (Immunohiostchemistry)
(Anti-Stefin B antibody, AAA45690, IHC(P)IHC(P): Human Lung Cancer Tissue)
WB (Western Blot)
(Anti-Stefin B antibody, AAA45690, Western blottingLane 1: A549 Cell LysateLane 2: A431 Cell LysateLane 3: COLO320 Cell LysateLane 4: HELA Cell Lysate)
WB (Western Blot)
(Anti-Stefin B antibody, AAA45690, Western blottingLane 1: A549 Cell LysateLane 2: A431 Cell LysateLane 3: COLO320 Cell LysateLane 4: HELA Cell Lysate)
Related Product Information for anti-CSTB antibody
Description: Rabbit IgG polyclonal antibody for Cystatin-B(CSTB) detection. Tested with WB, IHC-P in Human.
Background: Cystatin B(CSTB),also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is though to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.
Background: Cystatin B(CSTB),also called STFB, is a small protein that is a member of the superfamily of cysteine protease inhibitors. It has been isolated from human spleen and liver and its amino acid sequence has been fully determined. The cystatin B gene is located on 21q22.3. It is widely distributed and is localized mostly intracellularly, but has been found extracellularly. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Its role is though to be as a protector against the proteinases leaking from lysosomes. A cystatin B multiprotein complex might have a specific cerebellar function, and that the loss of this function might contribute to the etiopathogenesis of EPM1. Upon differentiation to myotubes, CSTB becomes excluded from the nucleus and lysosomes, suggesting that the subcellular distribution of CSTB is dependent on the differentiation status of the cell.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
11,140 Da
NCBI Official Full Name
Cystatin-B
NCBI Official Synonym Full Names
cystatin B (stefin B)
NCBI Official Symbol
CSTB
NCBI Official Synonym Symbols
PME; ULD; CST6; EPM1; STFB; EPM1A
NCBI Protein Information
cystatin-B; CPI-B; liver thiol proteinase inhibitor
UniProt Protein Name
Cystatin-B
UniProt Gene Name
CSTB
UniProt Synonym Gene Names
CST6; STFB
UniProt Entry Name
CYTB_HUMAN
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Product Notes
The CSTB cstb (Catalog #AAA45690) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Stefin B antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Stefin B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the CSTB cstb for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Stefin B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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