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IP (Immunoprecipitation)
(Immunoprecipitation analysis of 200ug extracts of HeLa cells usingug STRAP Polyclonal Antibody.Western blot was performed from the immunoprecipitate using STRAP Polyclonal Antibody at a dilution of 1:1000.)
Rabbit anti-Human, Mouse STRAP Polyclonal Antibody | anti-STRAP antibody
STRAP Polyclonal Antibody
Gene Names
STRAP; MAWD; PT-WD; UNRIP
Reactivity
Human, Mouse
Applications
Immunoprecipitation, Immunofluorescence, Western Blot
Purity
Affinity purification
Synonyms
STRAP, Antibody; STRAP Polyclonal Antibody; STRAP; MAWD; PT-WD; UNRIP; serine-threonine kinase receptor-associated protein; anti-STRAP antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration
1mg/mL (varies by lot)
Applicable Applications for anti-STRAP antibody
IP (Immunoprecipitation), IF (Immunofluorescence), WB (Western Blot)
Immunogen
Recombinant fusion protein of human STRAP
Research Area
Epigenetics and Nuclear Signaling
Preparation and Storage
Storage: -20 degree C/One year. Avoid freeze/thaw cycles.
IP (Immunoprecipitation)
(Immunoprecipitation analysis of 200ug extracts of HeLa cells usingug STRAP Polyclonal Antibody.Western blot was performed from the immunoprecipitate using STRAP Polyclonal Antibody at a dilution of 1:1000.)
IP (Immunoprecipitation)
(Immunoprecipitation analysis of 200ug extracts of HeLa cells usingug STRAP Polyclonal Antibody.Western blot was performed from the immunoprecipitate using STRAP Polyclonal Antibody at a dilution of 1:1000.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of U2OS cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of L929 cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of L929 cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of H9C2 cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
IF (Immunofluorescence)
(Immunofluorescence analysis of H9C2 cells using [KO Validated] STRAP Polyclonal Antibody at dilution of 100 (40x lens). Blue: DAPI for nuclear staining.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using STRAP Polyclonal Antibody at 1:1000 dilution.)
WB (Western Blot)
(Western blot analysis of extracts of various cell lines using STRAP Polyclonal Antibody at 1:1000 dilution.)
Related Product Information for anti-STRAP antibody
The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs, the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.
Product Categories/Family for anti-STRAP antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
39,778 Da
NCBI Official Full Name
serine-threonine kinase receptor-associated protein
NCBI Official Synonym Full Names
serine/threonine kinase receptor associated protein
NCBI Official Symbol
STRAP
NCBI Official Synonym Symbols
MAWD; PT-WD; UNRIP
NCBI Protein Information
serine-threonine kinase receptor-associated protein
UniProt Protein Name
Serine-threonine kinase receptor-associated protein
UniProt Gene Name
STRAP
UniProt Synonym Gene Names
MAWD; UNRIP
UniProt Entry Name
STRAP_HUMAN
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Product Notes
The STRAP strap (Catalog #AAA179320) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STRAP Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's STRAP can be used in a range of immunoassay formats including, but not limited to, IP (Immunoprecipitation), IF (Immunofluorescence), WB (Western Blot). Researchers should empirically determine the suitability of the STRAP strap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "STRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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