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product-image-AAA119310_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human colon cancer using AAA119310 at dilution 1:100)

Rabbit anti-Human Structural maintenance of chromosomes protein 1A Polyclonal Antibody | anti-SMC1A antibody

Rabbit anti-human Structural maintenance of chromosomes protein 1A polyclonal Antibody(SMC1A)

Gene Names
SMC1A; SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha
Reactivity
Human
Applications
Immunohistochemistry, ELISA
Purity
Antigen Affinity Purified
Synonyms
Structural maintenance of chromosomes protein 1A, Antibody; Rabbit anti-human Structural maintenance of chromosomes protein 1A polyclonal Antibody(SMC1A); SMC protein 1A; SMC-1-alpha; SMC-1A; Sb1.8; SMC1A; DXS423E; KIAA0178; SB1.8; SMC1; SMC1L1; anti-SMC1A antibody
Ordering
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Sequence Length
1233
Applicable Applications for anti-SMC1A antibody
IHC (Immunohistochemistry), ELISA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Conjugate
Non-conjugated
Immunogen
Recombinant human Structural maintenance of chromosomes protein 1A protein(1-130aa)
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-10707 / sc-30958 / sc-30959 / sc-30960 / sc-10706 / sc-21078 / sc-56776 / sc-25387
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

IHC (Immunohistochemisry)

(Immunohistochemistry of paraffin-embedded human colon cancer using AAA119310 at dilution 1:100)

product-image-AAA119310_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochemistry of paraffin-embedded human colon cancer using AAA119310 at dilution 1:100)

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human rectal cancer using AAA119310 at dilution 1:100)

product-image-AAA119310_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human rectal cancer using AAA119310 at dilution 1:100)

IHC (Immunohistochemistry)

(Immunohistochemistry of paraffin-embedded human tonsil using AAA119310 at dilution 1:100)

product-image-AAA119310_IHC15.jpg IHC (Immunohistochemistry) (Immunohistochemistry of paraffin-embedded human tonsil using AAA119310 at dilution 1:100)
Related Product Information for anti-SMC1A antibody
Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
143,233 Da
NCBI Official Full Name
structural maintenance of chromosomes protein 1A isoform 1
NCBI Official Synonym Full Names
structural maintenance of chromosomes 1A
NCBI Official Symbol
SMC1A
NCBI Official Synonym Symbols
SMC1; SMCB; CDLS2; SB1.8; SMC1L1; DXS423E; SMC1alpha
NCBI Protein Information
structural maintenance of chromosomes protein 1A
UniProt Protein Name
Structural maintenance of chromosomes protein 1A
UniProt Gene Name
SMC1A
UniProt Synonym Gene Names
DXS423E; KIAA0178; SB1.8; SMC1; SMC1L1; SMC protein 1A; SMC-1-alpha; SMC-1A
UniProt Entry Name
SMC1A_HUMAN

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Product Notes

The SMC1A smc1a (Catalog #AAA119310) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human Structural maintenance of chromosomes protein 1A polyclonal Antibody(SMC1A) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Structural maintenance of chromosomes protein 1A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the SMC1A smc1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Structural maintenance of chromosomes protein 1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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