ICC (Immunocytochemistry)
(Immunocytochemistry of SUSD3 in 3T3 cells with SUSD3 antibody at 5 μg/ml.)
Rabbit anti-Human, Mouse SUSD3 Polyclonal Antibody | anti-SUSD3 antibody
SUSD3 Antibody
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column.
Synonyms
SUSD3, Antibody; SUSD3 Antibody; Sushi domain containing 3; anti-SUSD3 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
SUSD3 antibody is human and mouse reactive. Multiple isoforms of SUSD3 are known to exist.
Purity/Purification
Affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
255
Applicable Applications for anti-SUSD3 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen
SUSD3 antibody was raised against a 16 amino acid peptide from near the center of human SUSD3.
Buffer
Supplied in PBS containing 0.02% sodium azide.
Positive Control 1
3T3 Cell Lysate
Conjugate
Unconjugated
Preparation and Storage
Store at 4 degree C for three months and -20 degree C, stable for up to one year.
ICC (Immunocytochemistry)
(Immunocytochemistry of SUSD3 in 3T3 cells with SUSD3 antibody at 5 μg/ml.)
ICC (Immunocytochemistry)
(Immunocytochemistry of SUSD3 in 3T3 cells with SUSD3 antibody at 5 μg/ml.)
WB (Western Blot)
(Western blot analysis of SUSD3 in HeLa cell lysate with SUSD3 antibody at 1 μg/ml.)
WB (Western Blot)
(Western blot analysis of SUSD3 in HeLa cell lysate with SUSD3 antibody at 1 μg/ml.)
Related Product Information for anti-SUSD3 antibody
Little is known of the function of the sushi domain containing 3 protein (SUSD3), but its expression has been reported in estrogen receptor-alpha (ERalpha)-positive breast tumors with decreased expression reported in aggressive malignant tumors (1,2). Recently, SUSD3 has been found to promote estrogen-dependent cell proliferation and may regulate cell-cell and cell-substrate interactions and migration in breast cancer (3). Furthermore, elevated SUSD3 mRNA levels were observed in aromatase inhibitor-responsive breast tumors, suggesting that it may also serve as a novel predictor of response to endocrine therapy and a potential therapeutic target (3).
Product Categories/Family for anti-SUSD3 antibody
References
Abba MC, Hu Y, Sun H, et al. Gene expression signature of estrogen receptor alpha status in breast cancer. BMC Genomics 2005; 6:37. Parris TZ, Danielsson A, Nemes S, et al. Clinical implications of gene dosage and gene expression patterns in diploid breast cancer. Clin. Cancer Res. 2010; 16:3860-74. Moy I, Todorovic V, Dubash AD, et al. Estrogen-dependent sushi domain containing 3 regulates cytoskeleton organization and migration in breast cancer cells. Oncogene 2015; 34:323-33.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
Predicted: 16, 22, 23, 28 kDa
Observed: 23 kDa
Observed: 23 kDa
NCBI Official Full Name
sushi domain-containing protein 3 isoform a
NCBI Official Synonym Full Names
sushi domain containing 3
NCBI Official Symbol
SUSD3
NCBI Protein Information
sushi domain-containing protein 3
UniProt Protein Name
Sushi domain-containing protein 3
UniProt Gene Name
SUSD3
UniProt Entry Name
SUSD3_HUMAN
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Product Notes
The SUSD3 susd3 (Catalog #AAA40833) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SUSD3 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's SUSD3 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SUSD3 susd3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SUSD3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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