IHC (Immunohiostchemistry)
(Immunohistochemistry of Syntaphilin in human brain with Syntaphilin antibody at 5 ug/mL.)
Rabbit Syntaphilin Polyclonal Antibody | anti-SNPH antibody
Syntaphilin Antibody
Gene Names
SNPH; bA314N13.5
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
Syntaphilin, Antibody; Syntaphilin Antibody; SNPH; anti-SNPH antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
494
Applicable Applications for anti-SNPH antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 18 amino acid peptide from near the amino terminus of human Syntaphilin.
Target Name
Syntaphilin
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of Syntaphilin in human brain with Syntaphilin antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of Syntaphilin in human brain with Syntaphilin antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of Syntaphilin in human brain tissue lysate with Syntaphilin antibody at (A) 2 and (B) 4 ug/mL.)
WB (Western Blot)
(Western blot analysis of Syntaphilin in human brain tissue lysate with Syntaphilin antibody at (A) 2 and (B) 4 ug/mL.)
Related Product Information for anti-SNPH antibody
Syntaphilin was initially identified in a yeast two-hybrid screen with the carboxy terminal region of Syntaxin-1 as bait. Syntaxin-1 is a key component of the synaptic vesicle docking machinery that forms the SNARE complex with synaptobrevin and SNAP-25. Syntaphilin competes with SNAP-25 for binding to syntaxin-1 and inhibits the formation of the SNARE complex, thereby potentially regulating synaptic vesicle exocytosis. Syntaphilin also binds dynamin-1 and inhibits dynamin-dependent endocytosis. Mice lacking syntaphilin show an increased level of mitochondrial motility and a reduced density of axonal mitochondria. This correlates with an enhanced short-term facilitation and significant impairments in motor ability, suggesting syntaphilin plays a major role in presynaptic function. Multiple isoforms are known to exist.
Product Categories/Family for anti-SNPH antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
57,990 Da
NCBI Official Full Name
syntaphilin
NCBI Official Synonym Full Names
syntaphilin
NCBI Official Symbol
SNPH
NCBI Official Synonym Symbols
bA314N13.5
NCBI Protein Information
syntaphilin
UniProt Protein Name
Syntaphilin
UniProt Gene Name
SNPH
UniProt Synonym Gene Names
KIAA0374
UniProt Entry Name
SNPH_HUMAN
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Product Notes
The SNPH snph (Catalog #AAA301011) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Syntaphilin Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Syntaphilin can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the SNPH snph for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Syntaphilin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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