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product-image-AAA286083_IHC13.jpg IHC (Immunohiostchemistry) (SYT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Rabbit SYT1 Polyclonal Antibody | anti-SYT1 antibody

SYT1 Antibody (C-term)

Gene Names
SYT1; P65; SYT; SVP65
Reactivity
Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Rat)
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
SYT1, Antibody; SYT1 Antibody (C-term); Synaptotagmin-1; Synaptotagmin I; SytI; p65; SYT1; SVP65; SYT; anti-SYT1 antibody
Ordering
Host
Rabbit
Reactivity
Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Rat)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This SYT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349-377 amino acids from the C-terminal region of human SYT1.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.41 (varies by lot)
Sequence Positions
349-377
Sequence Length
422
Applicable Applications for anti-SYT1 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

IHC (Immunohiostchemistry)

(SYT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

product-image-AAA286083_IHC13.jpg IHC (Immunohiostchemistry) (SYT1 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SYT1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

WB (Western Blot)

(SYT1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SYT1 antibody detected the SYT1 protein (arrow).)

product-image-AAA286083_WB15.jpg WB (Western Blot) (SYT1 Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the SYT1 antibody detected the SYT1 protein (arrow).)
Related Product Information for anti-SYT1 antibody
The synaptotagmins are integral membrane proteins of
synaptic vesicles thought to serve as Ca(2+) sensors in the process
of vesicular trafficking and exocytosis. Calcium binding to
synaptotagmin-1 participates in triggering neurotransmitter release
at the synapse (Fernandez-Chacon et al., 2001 [PubMed
11242035]).
Product Categories/Family for anti-SYT1 antibody
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Musch, M.W., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (2), G203-G211 (2010) :
Kathir, K.M., et al. Biochim. Biophys. Acta 1798(2):297-302(2010)
Pattaro, C., et al. BMC Med. Genet. 11, 41 (2010) :
Hamdan, F.F., et al. Ann. Neurol. 65(6):748-753(2009)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
47573
NCBI Official Full Name
synaptotagmin-1 isoform 1
NCBI Official Synonym Full Names
synaptotagmin I
NCBI Official Symbol
SYT1
NCBI Official Synonym Symbols
P65; SYT; SVP65
NCBI Protein Information
synaptotagmin-1
UniProt Protein Name
Synaptotagmin-1
UniProt Gene Name
SYT1
UniProt Synonym Gene Names
SVP65; SYT; SytI
UniProt Entry Name
SYT1_HUMAN

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Product Notes

The SYT1 syt1 (Catalog #AAA286083) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 349-377. The SYT1 Antibody (C-term) reacts with Human (Predicted Reactivity: Bovine, Chicken, Monkey, Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's SYT1 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the SYT1 syt1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SYT1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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