ICC (Immunocytochemistry)
(Immunocytochemistry of TAB1 in K562 cells with TAB1 antibody at 1 ug/mL.)
Rabbit anti-Human, Mouse TAB1 Polyclonal Antibody | anti-TAB1 antibody
TAB1 Antibody
Gene Names
TAB1; 3'-Tab1; MAP3K7IP1
Reactivity
Human, Mouse
Applications
Immunocytochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
TAB1, Antibody; TAB1 Antibody; anti-TAB1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
504
Applicable Applications for anti-TAB1 antibody
ICC (Immunocytochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a synthetic peptide corresponding to 13 amino acids in the center of human TAB1.
Target Name
TAB1
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
ICC (Immunocytochemistry)
(Immunocytochemistry of TAB1 in K562 cells with TAB1 antibody at 1 ug/mL.)
ICC (Immunocytochemistry)
(Immunocytochemistry of TAB1 in K562 cells with TAB1 antibody at 1 ug/mL.)
WB (Western Blot)
(Western blot analysis of TAB1 in 3T3 cell lysate with TAB1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of TAB1 in 3T3 cell lysate with TAB1 antibody at (A) 0.5, (B) 1, and (C) 2 ug/mL.)
Related Product Information for anti-TAB1 antibody
TAB1 was identified as a regulator of the MAP kinase kinase kinase TAK1/MAP3K7, which is known to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. This protein, together with either TAB2 or TAB3, activates TAK1 kinase in response to upstream signals. It has been shown that the C-terminal portion of TAB1 is sufficient for binding and activation of TAK1, while a portion of the N-terminus acts as a dominant-negative inhibitor of TGF-beta, demonstrating how this protein can function as a mediator between TGF-beta receptors and TAK1.
Product Categories/Family for anti-TAB1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,917 Da
NCBI Official Full Name
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 isoform alpha
NCBI Official Synonym Full Names
TGF-beta activated kinase 1/MAP3K7 binding protein 1
NCBI Official Symbol
TAB1
NCBI Official Synonym Symbols
3'-Tab1; MAP3K7IP1
NCBI Protein Information
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
UniProt Protein Name
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1
UniProt Gene Name
TAB1
UniProt Synonym Gene Names
MAP3K7IP1; TAK1-binding protein 1
UniProt Entry Name
TAB1_HUMAN
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Product Notes
The TAB1 tab1 (Catalog #AAA306440) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TAB1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TAB1 can be used in a range of immunoassay formats including, but not limited to, ICC (Immunocytochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TAB1 tab1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAB1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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