Rabbit TAZ Polyclonal Antibody | anti-TAFAZZIN antibody
Anti-TAZ Antibody
After date of receipt, stable for at least 1 year at -20 degree C.
WB (Western Blot)
(Western Blot: Upper, 3D cancer spheroids were harvested for WB for CTGF. VASP knockdown reduced CTGF protein levels in KM12L4 and L3.6 cells. Lower, cells on Matrigel were treated with PF-228 (3uM) and collected for WB. PF-228 reduced YAP1/TAZ protein levels. Samples derived from the same experiment and gels/blots were processed in parallel. Image from the following publication (//www.nature.com/articles/s41698-017-0045-7) licensed under a CC-BY license.)
Highly conserved and ubiquitously expressed 14-3-3 proteins regulate differentiation, cell cycle progression and apoptosis by binding intracellular phosphoproteins involved in signal transduction. A novel transcriptional co-activator, TAZ (transcriptional co-activator with PDZ-binding motif) functions as a 14-3-3-binding molecule. TAZ may link events at the plasma membrane and cytoskeleton to nuclear transcription in a manner that can be regulated by 14-3-3.
NCBI and Uniprot Product Information
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Product Notes
The TAFAZZIN taz (Catalog #AAA72765) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TAZ Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAZ can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot). Researchers should empirically determine the suitability of the TAFAZZIN taz for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAZ, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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