Rabbit anti-Human TCCR Polyclonal Antibody | anti-IL27RA antibody

TCCR Antibody

Cat. Num. AAA40148

• Gene Names: IL27RA; CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
• Reactivity: Human
• Applications: Immunofluorescence, Immunohistochemistry, Western Blot, ELISA
• Purity: TCCR Antibody is affinity chromatography purified via peptide column.
• Synonyms: TCCR, Antibody; TCCR Antibody; TCCR; CRL1; WSX1; IL27R; IL-27RA; zcytor1; UNQ296/PRO336; Interleukin-27 receptor subunit alpha; Cytokine receptor WSX-1; IL-27 receptor subunit alpha; interleukin 27 receptor, alpha; anti-IL27RA antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TCCR Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Sequence Length: 636

• Applicable Applications for anti-IL27RA antibody: IF (Immunofluorescence), IHC (Immunohistochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TCCR antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor.
• Buffer: TCCR Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TCCR antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TCCR in A549 cells with TCCR antibody at 20 μg/mL.)

IHC (Immunohiostchemistry)

(Immunohistochemistry of TCCR in human spleen tissue with TCCR antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of TCCR expression in human spleen tissue lysates with TCCR antibody at 1 μg /ml.)

Related Product Information for anti-IL27RA antibody

TCCR Antibody: Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

NCBI and Uniprot Product Information

• NCBI GI #: 4759328
• NCBI GeneID: 9466
• NCBI Accession #: NP_004834
• NCBI GenBank Nucleotide #: NM_004843.3
• UniProt Accession #: Q6UWB1; O60624; A0N0L1
• Molecular Weight: 70 kDa
• NCBI Official Full Name: interleukin-27 receptor subunit alpha
• NCBI Official Synonym Full Names: interleukin 27 receptor, alpha
• NCBI Official Symbol: IL27RA
• NCBI Official Synonym Symbols: CRL1; TCCR; WSX1; IL27R; IL-27RA; zcytor1
• NCBI Protein Information: interleukin-27 receptor subunit alpha; IL-27R-alpha; IL-27R subunit alpha; cytokine receptor WSX-1; cytokine receptor-like 1; class I cytokine receptor; IL-27 receptor subunit alpha; T-cell cytokine receptor type 1; type I T-cell cytokine receptor
• UniProt Protein Name: Interleukin-27 receptor subunit alpha
• UniProt Gene Name: IL27RA
• UniProt Synonym Gene Names: CRL1; TCCR; WSX1; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; TCCR
• UniProt Entry Name: I27RA_HUMAN