Rabbit anti-Human TEAD2 Polyclonal Antibody | anti-TEAD2 antibody
TEAD2 Antibody
Gene Names
TEAD2; ETF; TEF4; TEF-4; TEAD-2
Reactivity
Human
Applications
Immunofluorescence, Immunohistochemistry
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
TEAD2, Antibody; TEAD2 Antibody; TEA domain family member 2; TEAD-2; anti-TEAD2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total TEAD2 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
450
Applicable Applications for anti-TEAD2 antibody
IF (Immunofluorescence), IHC (Immunohistochemistry)
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human TEAD2.
Target Name
TEAD2
Preparation and Storage
Store at -20 degree C
Related Product Information for anti-TEAD2 antibody
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.The MGC Project Team, Genome Res. 14:2121-2127(2004). Jacquemin P., J. Biol. Chem. 271:21775-21785(1996).
Product Categories/Family for anti-TEAD2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
49,640 Da
NCBI Official Full Name
transcriptional enhancer factor TEF-4 isoform 1
NCBI Official Synonym Full Names
TEA domain family member 2
NCBI Official Symbol
TEAD2
NCBI Official Synonym Symbols
ETF; TEF4; TEF-4; TEAD-2
NCBI Protein Information
transcriptional enhancer factor TEF-4
UniProt Protein Name
Transcriptional enhancer factor TEF-4
UniProt Gene Name
TEAD2
UniProt Synonym Gene Names
TEF4; TEAD-2
UniProt Entry Name
TEAD2_HUMAN
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Product Notes
The TEAD2 tead2 (Catalog #AAA302707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TEAD2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TEAD2 can be used in a range of immunoassay formats including, but not limited to, IF (Immunofluorescence), IHC (Immunohistochemistry). Researchers should empirically determine the suitability of the TEAD2 tead2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TEAD2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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