Rabbit anti-Mouse, Rat TEM7 Polyclonal Antibody | anti-TEM7 antibody

RABBIT ANTI TEM7

Cat. Num. AAA50076

• Gene Names: PLXDC1; TEM3; TEM7
• Reactivity: Mouse, Rat
• Applications: Western Blot, Immunohistochemistry
• Synonyms: TEM7, Antibody; RABBIT ANTI TEM7; anti-TEM7 antibody

• Host: Rabbit
• Reactivity: Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: This item recognises human Tumour endothelial marker 7 (TEM7), a 55.8 kDa protein belonging to the plexin family. ; ; TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. ; ; Studies have indicated the existence of least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. ; ; TEM7 is not detectable in endothelial cells from normal tissues.
• Form/Format: Purified; Purified IgG - liquid
• Concentration: IgG concentration 1.0mg/ml (varies by lot)
• Sequence Length: 500

• Applicable Applications for anti-TEM7 antibody: WB (Western Blot), IHC (Immunohistochemistry)
• Perservative Stabilisers: 0.02% Sodium Azide (NaN3)
• Immunogen: A peptide corresponding to a 16 amino acid sequence from near the center of human TEM7.; Histology Positive Control Tissue
• Antiserum Preparation: Antiserum to human TEM7 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
• Target Species: Human
• Preparation and Storage: Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.; Shelf Life: 18 months from date of despatch.

Application Data

(Immunohistochemical staining of mouse liver with Rabbit anti Human TEM7 (AAA50076) at 2.5ug/ml)

Application Data

(Western blot analysis of rat liver lysate probed with Rabbit anti Human TEM7 (AAA50076) at 0.5(A) and 1(B) ug/ml)

Related Product Information for anti-TEM7 antibody

MBS223982 recognises human Tumour endothelial marker 7 (TEM7), a 55.8 kDa protein belonging to the plexin family. TEM7 is strongly expressed in endothelial cells from colorectal cancer and from primary cancers of the lung, liver, brain, breast and pancreas. High expression of TEM7 is associated with metastasis and poor survival of patients with osteogenic sarcoma. Studies have indicated the existence of least four isoforms of TEM7 which include membrane bound, secreted and intracellular forms. TEM7 is not detectable in endothelial cells from normal tissues.

NCBI and Uniprot Product Information

• NCBI GI #: 15011862
• NCBI GeneID: 57125
• NCBI Accession #: NP_065138.2
• NCBI GenBank Nucleotide #: NM_020405.4
• UniProt Accession #: Q8IUK5; Q5QCZ7; Q5QCZ8; Q5QCZ9; Q9HCT9; B2R7I8
• Molecular Weight: 47,895 Da
• NCBI Official Full Name: plexin domain-containing protein 1
• NCBI Official Synonym Full Names: plexin domain containing 1
• NCBI Official Symbol: PLXDC1
• NCBI Official Synonym Symbols: TEM3; TEM7
• NCBI Protein Information: plexin domain-containing protein 1; 2410003I07Rik; tumor endothelial marker 3; tumor endothelial marker 7
• UniProt Protein Name: Plexin domain-containing protein 1
• UniProt Gene Name: PLXDC1
• UniProt Synonym Gene Names: TEM3; TEM7
• UniProt Entry Name: PLDX1_HUMAN