Rabbit anti-Mouse Thy1/CD90 Polyclonal Antibody | anti-THY1 antibody

Anti-Thy1/CD90 Antibody, Rabbit Polyclonal

Cat. Num. AAA257161

• Gene Names: Thy1; T25; CD90; Thy-1; Thy1.1; Thy1.2; Thy-1.2
• Reactivity: Mouse
• Applications: Immunohistochemistry, ELISA
• Purity: Protein A & Antigen Affinity
• Synonyms: Thy1/CD90, Antibody; Anti-Thy1/CD90 Antibody, Rabbit Polyclonal; CD90/THY-1 Antibody, Rabbit PAb, Antigen Affinity Purified; Thy-1 cell surface antigen; Anti-CD90 Antibody; Anti-T25 Antibody; Anti-Thy-1 Antibody; Anti-Thy-1.2 Antibody; Anti-Thy1.1 Antibody; Anti-Thy1.2 Antibody; anti-THY1 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Mouse THY1/CD90
• Purity/Purification: Protein A & Antigen Affinity
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-THY1 antibody: IHC (Immunohistochemistry), ELISA
• Immunogen: Recombinant Mouse THY1 protein
• Conjugation: Unconjugated
• Preparation: Produced in rabbits immunized with purified, recombinant Mouse THY1 (rM THY1). THY1 specific IgG was purified by mouse THY1 affinity chromatography .
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

IHC (Immunohistochemisry)

(Immunochemical staining of mouse THY1 in rat brain with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections).)

IHC (Immunohiostchemistry)

(Immunochemical staining of mouse THY1 in rat kidney with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). Positive staining was localized to renal glomerulus.)

IHC (Immunohistochemistry)

(Immunochemical staining of mouse THY1 in rat retina with rabbit polyclonal antibody (1:2000, formalin-fixed paraffin embedded sections). Positive staining was localized to ganglion cells.)

Related Product Information for anti-THY1 antibody

Thy-1 membrane glycoprotein, also known as Thy-1 antigen, CD90 and THY1, is a cell membrane protein which contains 1 Ig-like V-type (immunoglobulin-like) domain. It is a glycophosphatidylinositol-linked glycoprotein expressed on the surface of neurons, thymocytes, subsets of fibroblasts, endothelial cells, mesangial cells and some hematopoietic cells. It has been identified on a variety of stem cells and at varying levels in non-lymphoid tissues such as on fibroblasts, brain cells, and activated endothelial cells. Thy-1 is evolutionarily conserved, developmentally regulated, and often has dramatic effects on cell phenotype. Thy-1 is a 25-37 kDa glycosylphosphatidylinositol (GPI)-anchored protein involved in T cell activation, neurite outgrowth, apoptosis, tumor suppression, wound healing, and fibrosis. To mediate these diverse effects, Thy-1 participates in multiple signaling cascades. Thy-1 is an important regulator of cell-cell and cell-matrix interactions, with important roles in nerve regeneration, metastasis, inflammation, and fibrosis.

References

Rege TA, et al. (2006) Thy-1 as a regulator of cell-cell and cell-matrix interactions in axon regeneration, apoptosis, adhesion, migration, cancer, and fibrosis. FASEB J. 20(8): 1045-54.Fiegel HC, et al. (2008) Lack of Thy1 (CD90) expression in neuroblastomas is correlated with impaired survival. Pediatr Surg Int. 24(1): 101-5.Bradley JE, et al. (2009) Roles and regulation of Thy-1, a context-dependent modulator of cell phenotype. Biofactors. 35(3): 258-65.Kisselbach L, et al. (2009) CD90 Expression on human primary cells and elimination of contaminating fibroblasts from cell cultures. Cytotechnology. 59(1): 31-44.

NCBI and Uniprot Product Information

• NCBI GI #: 6678347
• NCBI GeneID: 21838
• NCBI Accession #: NP_033408.1
• NCBI GenBank Nucleotide #: NM_009382.3
• UniProt Accession #: P01831
• Molecular Weight: 18,080 Da
• NCBI Official Full Name: thy-1 membrane glycoprotein preproprotein
• NCBI Official Synonym Full Names: thymus cell antigen 1, theta
• NCBI Official Symbol: Thy1
• NCBI Official Synonym Symbols: T25; CD90; Thy-1; Thy1.1; Thy1.2; Thy-1.2
• NCBI Protein Information: thy-1 membrane glycoprotein; Thy 1.2; thy-1 antigen
• UniProt Protein Name: Thy-1 membrane glycoprotein
• UniProt Gene Name: Thy1
• UniProt Synonym Gene Names: Thy-1
• UniProt Entry Name: THY1_MOUSE