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Application Data
Rabbit TLR7 Polyclonal Antibody | anti-TLR7 antibody
Anti-TLR7 antibody
Gene Names
TLR7; TLR7-like
Reactivity
Human, Rat, Mouse
Applications
Immunohistochemistry, Western Blot
Purity
Immunogen affinity purified.
Synonyms
TLR7, Antibody; Anti-TLR7 antibody; Toll-like receptor 7; toll-like receptor 7; PRO285 antibody; TLR 7 antibody; Tlr7 antibody; TLR7_HUMAN antibody; Toll like receptor 7 antibody; Toll-like receptor 7 antibody; UNQ248 antibody; anti-TLR7 antibody
Host
Rabbit
Reactivity
Human, Rat, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Immunogen affinity purified.
Form/Format
Lyophilized
Sequence Length
1049
Applicable Applications for anti-TLR7 antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human TLR7 (1020-1038aa QAHPYFWQCLKNALATDNH), different from the related rat and mouse sequences by one amino acid.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Preparation and Storage
At -20 degree C for one year. After reconstitution, at 4 degree C for one month. It can also be aliquotted and stored frozen at -20 degree C for a longer time. Avoid repeated freezing and thawing.
Application Data
Application Data
IHC (Immunohistochemisry)
(Anti-TLR7 antibody, AAA45058, IHC(P)IHC(P): Rat Spleen Tissue)
IHC (Immunohistochemisry)
(Anti-TLR7 antibody, AAA45058, IHC(P)IHC(P): Rat Spleen Tissue)
IHC (Immunohiostchemistry)
(Anti-TLR7 antibody, AAA45058, IHC(P)IHC(P): Human Placenta Tissue)
IHC (Immunohiostchemistry)
(Anti-TLR7 antibody, AAA45058, IHC(P)IHC(P): Human Placenta Tissue)
WB (Western Blot)
(Anti-TLR7 antibody, AAA45058, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Liver Tissue LysateLane 3: U87 Cell LysateLane 4: A549 Cell Lysate)
WB (Western Blot)
(Anti-TLR7 antibody, AAA45058, Western blottingLane 1: Rat Spleen Tissue LysateLane 2: Rat Liver Tissue LysateLane 3: U87 Cell LysateLane 4: A549 Cell Lysate)
Related Product Information for anti-TLR7 antibody
Description: Rabbit IgG polyclonal antibody for Toll-like receptor 7(TLR7) detection. Tested with WB, IHC-P in Human, Rat, Mouse.
Background: TLR7(Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
Background: TLR7(Toll-like receptor 7) is protein that in humans is encoded by the TLR7 gene. Orthologs are found in mammals and birds. TLR7 is a member of the Toll-like receptor(TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns(PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on human chromosome X. TLR7 recognises single stranded RNA in endosomes, which is a common feature of viral genomes which are internalised by macrophages.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
120,922 Da
NCBI Official Full Name
Toll-like receptor 7
NCBI Official Synonym Full Names
toll-like receptor 7
NCBI Official Symbol
TLR7
NCBI Official Synonym Symbols
TLR7-like
NCBI Protein Information
toll-like receptor 7; toll-like receptor 7-like
UniProt Protein Name
Toll-like receptor 7
UniProt Gene Name
TLR7
UniProt Entry Name
TLR7_HUMAN
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Product Notes
The TLR7 tlr7 (Catalog #AAA45058) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-TLR7 antibody reacts with Human, Rat, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's TLR7 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TLR7 tlr7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR7, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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