Rabbit anti-Human, Mouse TLR8 Polyclonal Antibody | anti-TLR8 antibody

TLR8 Antibody

Cat. Num. AAA40297

• Gene Names: TLR8; CD288
• Reactivity: Human, Mouse
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: TLR8 Antibody is affinity chromatography purified via peptide column.
• Synonyms: TLR8, Antibody; TLR8 Antibody; TLR8; CD288; Toll-like receptor 8; toll-like receptor 8; anti-TLR8 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TLR8 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 1041

• Applicable Applications for anti-TLR8 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TLR8 antibody was raised against a peptide corresponding to 16 amino acids near the middle of human TLR8.
• Buffer: TLR8 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TLR8 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IF (Immunofluorescence)

(Immunofluorescence of TLR8 in Daudi cells with TLR8 antibody at 10 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of TLR8 in Daudi cells with TLR8 antibody at 2 μg/mL.)

WB (Western Blot)

(Western blot analysis of TLR8 in Daudi cell lysates with TLR8 antibody at (A) 0.5, (B) 1, and (C) 2 μg/mL.)

Related Product Information for anti-TLR8 antibody

TLR8 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors. Like TLR7, TLR8 is localized to endosomal or lysosomal compartments and stimulates the innate immune response after activation by guanosine- and uridine-rich single-stranded RNA. Human but not murine TLR8 confers responsiveness to the antiviral compound R-848.

NCBI and Uniprot Product Information

• NCBI GI #: 20302168
• NCBI GeneID: 51311
• NCBI Accession #: NP_619542
• NCBI GenBank Nucleotide #: NM_138636.5
• UniProt Accession #: Q9NR97; Q495P4; Q6UXL6; Q9NYG9; B3Y654; D1CS70; D1CS76
• Molecular Weight: 121,764 Da
• NCBI Official Full Name: toll-like receptor 8 isoform 2
• NCBI Official Synonym Full Names: toll-like receptor 8
• NCBI Official Symbol: TLR8
• NCBI Official Synonym Symbols: CD288
• NCBI Protein Information: toll-like receptor 8
• UniProt Protein Name: Toll-like receptor 8
• UniProt Gene Name: TLR8
• UniProt Entry Name: TLR8_HUMAN