IHC (Immunohiostchemistry)
(TLR8 Antibody (Center) (AAA285254)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TLR8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human TLR8 Polyclonal Antibody | anti-TLR8 antibody
TLR8 Antibody (Center)
Gene Names
TLR8; CD288
Reactivity
Human
Applications
Immunohistochemistry, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
TLR8, Antibody; TLR8 Antibody (Center); Toll-like receptor 8; CD288; TLR8; anti-TLR8 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This TLR8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 434-463 amino acids from the Central region of human TLR8.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
434-463
Sequence Length
1,059
Applicable Applications for anti-TLR8 antibody
IHC (Immunohistochemistry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
IHC (Immunohiostchemistry)
(TLR8 Antibody (Center) (AAA285254)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TLR8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
IHC (Immunohiostchemistry)
(TLR8 Antibody (Center) (AAA285254)immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of TLR8 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.)
WB (Western Blot)
(TLR8 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow).)
WB (Western Blot)
(TLR8 Antibody (Center) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the TLR8 antibody detected the TLR8 protein (arrow).)
Related Product Information for anti-TLR8 antibody
The protein encoded by this gene is a member of the
Toll-like receptor (TLR) family which plays a fundamental role in
pathogen recognition and activation of innate immunity. TLRs are
highly conserved from Drosophila to humans and share structural and
functional similarities. They recognize pathogen-associated
molecular patterns (PAMPs) that are expressed on infectious agents,
and mediate the production of cytokines necessary for the
development of effective immunity. The various TLRs exhibit
different patterns of expression. This gene is predominantly
expressed in lung and peripheral blood leukocytes, and lies in
close proximity to another family member, TLR7, on chromosome X.
Toll-like receptor (TLR) family which plays a fundamental role in
pathogen recognition and activation of innate immunity. TLRs are
highly conserved from Drosophila to humans and share structural and
functional similarities. They recognize pathogen-associated
molecular patterns (PAMPs) that are expressed on infectious agents,
and mediate the production of cytokines necessary for the
development of effective immunity. The various TLRs exhibit
different patterns of expression. This gene is predominantly
expressed in lung and peripheral blood leukocytes, and lies in
close proximity to another family member, TLR7, on chromosome X.
Product Categories/Family for anti-TLR8 antibody
References
Zannetti, C., et al. J. Biol. Chem. 285(45):34773-34780(2010)
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Cros, J., et al. Immunity 33(3):375-386(2010)
Enevold, C., et al. Mult. Scler. 16(8):942-949(2010)
Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Cros, J., et al. Immunity 33(3):375-386(2010)
Enevold, C., et al. Mult. Scler. 16(8):942-949(2010)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
119828
NCBI Official Full Name
toll-like receptor 8 isoform 2
NCBI Official Synonym Full Names
toll-like receptor 8
NCBI Official Symbol
TLR8
NCBI Official Synonym Symbols
CD288
NCBI Protein Information
toll-like receptor 8
UniProt Protein Name
Toll-like receptor 8
UniProt Gene Name
TLR8
UniProt Entry Name
TLR8_HUMAN
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Product Notes
The TLR8 tlr8 (Catalog #AAA285254) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 434-463. The TLR8 Antibody (Center) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's TLR8 can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TLR8 tlr8 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR8, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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