IHC (Immunohiostchemistry)
Rabbit TMEM16A Polyclonal Antibody | anti-TMEM16A antibody
TMEM16A Antibody
Gene Names
Ano1; Tmem16a
Reactivity
Monkey, Mouse, Rat
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry, ELISA
Synonyms
TMEM16A, Antibody; TMEM16A Antibody; ANO 1; Anoctamin 1; Anoctamin 1 calcium activated chloride channel; Ca2+ activated Cl- channel; Discovered on gastrointestinal stromal tumors protein 1; DOG 1; Membrane protein; Oral cancer overexpressed protein 2; ORAOV 2; TAOS2; Transmembrane protein 16A; Tumor-amplified and overexpressed sequence 2 antibody; anti-TMEM16A antibody
Host
Rabbit
Reactivity
Monkey, Mouse, Rat
Clonality
Polyclonal
Form/Format
Affinity Purified
Concentration
0.50 ug/ul in antibody stabilization buffer (varies by lot)
Sequence Length
960
Applicable Applications for anti-TMEM16A antibody
WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA
Immunogen
Synthetic peptide taken within amino acid region on 70-120 on mouse Transmembrane Protein 16A.
Expression
Highly expressed in pulmonary bronchiole epithelial cells, pancreatic and submandibular gland acinar cells, kidney proximal tubule, all retinal cell layers, most sensory cells of dorsal root ganglia, Leydig cells and spermatocytes (at protein level). Expressed at high levels in the thyroid gland and gastrointestinal muscles.
Determinant
N-epitope
Molecular Function
Chloride channel, Developmental protein, Ion channel
Structure
Homodimer. Interacts with CFTR.
Subcellular Location
Cell membrane; Multi-pass membrane protein, Cytoplasm
Preparation and Storage
-20 degree C for long term storage
IHC (Immunohiostchemistry)
IHC (Immunohiostchemistry)
WB (Western Blot)
WB (Western Blot)
Related Product Information for anti-TMEM16A antibody
Affinity Purified Transmembrane protein 16A Antibody N-epitope
Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Calcium-activated chloride channel (CaCC) which plays an important role in transepithelial anion transport and smooth muscle contraction. Required for the normal functioning of the interstitial cells of Cajal (ICCs) which generate electrical pacemaker activity in gastrointestinal smooth muscles. Acts as a major contributor to basal and stimulated chloride conductance in airway epithelial cells and plays an important role in tracheal cartilage development.
Product Categories/Family for anti-TMEM16A antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
110,489 Da
NCBI Official Full Name
Anoctamin-1
NCBI Official Synonym Full Names
anoctamin 1, calcium activated chloride channel
NCBI Official Symbol
Ano1
NCBI Official Synonym Symbols
Tmem16a
NCBI Protein Information
anoctamin-1
UniProt Protein Name
Anoctamin-1
UniProt Gene Name
Ano1
UniProt Synonym Gene Names
Tmem16a
UniProt Entry Name
ANO1_MOUSE
Similar Products
Product Notes
The TMEM16A ano1 (Catalog #AAA75731) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM16A Antibody reacts with Monkey, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM16A can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), IP (Immunoprecipitation), IHC (Immunohistochemistry), ELISA. Researchers should empirically determine the suitability of the TMEM16A ano1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM16A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.