IHC (Immunohiostchemistry)
(Immunohistochemistry of TMEM38B in mouse thymus tissue with TMEM38B antibody at 5 ug/mL.)
Rabbit TMEM38B Polyclonal Antibody | anti-TMEM38B antibody
TMEM38B Antibody
Gene Names
TMEM38B; OI14; TRICB; TRIC-B; C9orf87; D4Ertd89e; bA219P18.1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
TMEM38B, Antibody; TMEM38B Antibody; Transmembrane protein 38B, TRIC-B, TRICB, trimeric cation channel type B; anti-TMEM38B antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
291
Applicable Applications for anti-TMEM38B antibody
IHC (Immunohistochemistry), WB (Western Blot), ELISA
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide from near the carboxy terminus of human TMEM38B.
Target Name
TMEM38B
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
IHC (Immunohiostchemistry)
(Immunohistochemistry of TMEM38B in mouse thymus tissue with TMEM38B antibody at 5 ug/mL.)
IHC (Immunohiostchemistry)
(Immunohistochemistry of TMEM38B in mouse thymus tissue with TMEM38B antibody at 5 ug/mL.)
WB (Western Blot)
(Western blot analysis of TMEM38B in rat thymus tissue lysate with TMEM38B antibody at (A) 1 and (B) 2 ug/mL.)
WB (Western Blot)
(Western blot analysis of TMEM38B in rat thymus tissue lysate with TMEM38B antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-TMEM38B antibody
TMEM38A and TMEM38B are two recently identified trimeric intracellular cation (TRIC) channel subtypes. TMEM38B is expressed in most mammalian tissues, while TMEM38A is preferentially expressed in excitable tissues such as striated muscle and brain. Mice deficient in both TMEM38A and TMEM38B suffer embryonic cardiac failure; the cardiac myocytes display severe dysfunction in SR Ca2+ handling, weakened Ca2+ release, and reduced K+ permeability indicating that the TRIC cation channels are likely to act as counter-ion channels that function in synchronization with Ca2+ release from intracellular stores. Mice that were lacking only TMEM38B however, die shortly after birth due to respiratory failure and have lungs exhibiting severe histological defect and ultrastructural abnormalities in their alveolar type II epithelial cells, indicating that TMEM38B are essential for perinatal lung maturation. Other experiments have shown that TMEM38A and TMEM38B can act with junctophilin proteins to support efficient ryanodine receptor-mediated Ca2+ release in muscle cells.
Product Categories/Family for anti-TMEM38B antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
32,510 Da
NCBI Official Full Name
trimeric intracellular cation channel type B
NCBI Official Synonym Full Names
transmembrane protein 38B
NCBI Official Symbol
TMEM38B
NCBI Official Synonym Symbols
OI14; TRICB; TRIC-B; C9orf87; D4Ertd89e; bA219P18.1
NCBI Protein Information
trimeric intracellular cation channel type B
UniProt Protein Name
Trimeric intracellular cation channel type B
UniProt Gene Name
TMEM38B
UniProt Synonym Gene Names
C9orf87; TRIC-B; TRICB
UniProt Entry Name
TM38B_HUMAN
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Product Notes
The TMEM38B tmem38b (Catalog #AAA304018) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TMEM38B Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TMEM38B can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TMEM38B tmem38b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TMEM38B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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