Rabbit anti-Human TNFRSF14 Polyclonal Antibody | anti-TNFRSF14 antibody

TNFRSF14 Antibody

Cat. Num. AAA39888

• Gene Names: TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
• Reactivity: Human
• Applications: Immunofluorescence, Immunocytochemistry, Western Blot, ELISA
• Purity: TNFRSF14 Antibody is affinity chromatography purified via peptide column.
• Synonyms: TNFRSF14, Antibody; TNFRSF14 Antibody; TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR; UNQ329/PRO509; Tumor necrosis factor receptor superfamily member 14; Herpes virus entry mediator A; Herpesvirus entry mediator A; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator); anti-TNFRSF14 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: TNFRSF14 Antibody is affinity chromatography purified via peptide column.
• Form/Format: Liquid
• Concentration: 1 mg/mL (varies by lot)
• Sequence Length: 283

• Applicable Applications for anti-TNFRSF14 antibody: IF (Immunofluorescence), ICC (Immunocytochemistry), WB (Western Blot), ELISA
• Conjugate: Unconjugated
• Immunogen: TNFRSF14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human TNFRSF14.
• Buffer: TNFRSF14 Antibody is supplied in PBS containing 0.02% sodium azide.
• Preparation and Storage: TNFRSF14 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

WB (Western Blot)

(Western blot analysis of 5 ng of TNFRSF14 with TNFRSF14 antibody at 1 μg/mL.)

IF (Immunofluorescence)

(Immunofluorescence of TNFRSF14 in Raji cells with TNFRSF14 antibody at 20 μg/mL.)

ICC (Immunocytochemistry)

(Immunocytochemistry of TNFRSF14 in Raji with TNFRSF14 antibody at 10 μg/mL.)

WB (Western Blot)

(Western blot analysis of TNFRSF14 in Raji cell lysate with TNFRSF14 antibody at 2 μg/mL in (A) the absence and (B) the presence of blocking peptide.)

Related Product Information for anti-TNFRSF14 antibody

TNFRSF14 Antibody: Tumor necrosis factor receptor (TNFR) superfamily members are defined by cysteine-rich domains in their extracellular regions that bind TNF-related ligands that share a common structural homology in their extracellular domain. TNFRSF14 was initially identified as the Herpesvirus entry mediator and upon binding to the herpes simplex virus (HSV) envelope glycoprotein D or either of its natural ligands LIGHT and lymphotoxin alpha (LT), activates the transcription factors NF-κB and AP-1. Activation of this signal transduction pathway in T cells stimulates T cell proliferation and cytokine production, leading to inflammation and enhanced CTL-mediated tumor immunity, suggesting that these proteins may be useful as potential targets for controlling cellular immune responses.

NCBI and Uniprot Product Information

• NCBI GI #: 13878821
• NCBI GeneID: 8764
• UniProt Accession #: Q92956; Q6IB95; Q8N634; Q8WXR1; Q96J31; Q9UM65; B3KW30; B9DI89
• Molecular Weight: 21,351 Da
• NCBI Official Full Name: Tumor necrosis factor receptor superfamily member 14
• NCBI Official Synonym Full Names: tumor necrosis factor receptor superfamily, member 14
• NCBI Official Symbol: TNFRSF14
• NCBI Official Synonym Symbols: TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
• NCBI Protein Information: tumor necrosis factor receptor superfamily member 14; CD40-like protein; herpes virus entry mediator A; tumor necrosis factor receptor-like gene2; tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)
• UniProt Protein Name: Tumor necrosis factor receptor superfamily member 14
• UniProt Gene Name: TNFRSF14
• UniProt Synonym Gene Names: HVEA; HVEM; Herpesvirus entry mediator A; HveA; TR2
• UniProt Entry Name: TNR14_HUMAN