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product-image-AAA286007_FCM13.jpg FCM/FACS (Flow Cytometry) (Tnks 2 Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Rabbit anti-Human, mouse Tnks 2 Polyclonal Antibody | anti-TNKS2 antibody

Tnks 2 Antibody (C-term)

Gene Names
TNKS2; TNKL; ARTD6; TANK2; pART6; PARP5B; PARP5C; PARP-5b; PARP-5c
Reactivity
Human, mouse
Applications
Flow Cytometry, Functional Assay, ELISA, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Tnks 2, Antibody; Tnks 2 Antibody (C-term); Tankyrase-2; TANK2; ADP-ribosyltransferase diphtheria toxin-like 6; ARTD6; Poly [ADP-ribose] polymerase 5B; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2; Tankyrase II; Tankyrase-like protein; Tankyrase-related protein; TNKS2; PARP5B; TNKL; anti-TNKS2 antibody
Ordering
Host
Rabbit
Reactivity
Human, mouse
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Tnks 2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1126-1156 amino acids from the C-terminal region of human Tnks 2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Concentration
Vial Concentration: 2 (varies by lot)
Sequence Positions
1126-1156
Sequence Length
1166
Applicable Applications for anti-TNKS2 antibody
FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot)
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

FCM/FACS (Flow Cytometry)

(Tnks 2 Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

product-image-AAA286007_FCM13.jpg FCM/FACS (Flow Cytometry) (Tnks 2 Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

WB (Western Blot)

(Tnks 2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Tnks 2 antibody detected Tnks 2 protein (arrow).)

product-image-AAA286007_WB15.jpg WB (Western Blot) (Tnks 2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Tnks 2 antibody detected Tnks 2 protein (arrow).)
Related Product Information for anti-TNKS2 antibody
Tnks 2 may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. Tnks 2 has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.
Product Categories/Family for anti-TNKS2 antibody
References
Varadi, V., et al. Eur. J. Cancer 45(17):3008-3016(2009)
Shebzukhov, Y.V., et al. Cancer Immunol. Immunother. 57(6):871-881(2008)
Sidorova, N.N., et al. Biochemistry Mosc. 73(3):289-295(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
126918
NCBI Official Full Name
tankyrase-2
NCBI Official Synonym Full Names
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
NCBI Official Symbol
TNKS2
NCBI Official Synonym Symbols
TNKL; ARTD6; TANK2; pART6; PARP5B; PARP5C; PARP-5b; PARP-5c
NCBI Protein Information
tankyrase-2
UniProt Protein Name
Tankyrase-2
UniProt Gene Name
TNKS2
UniProt Synonym Gene Names
PARP5B; TANK2; TNKL; TANK2; ARTD6
UniProt Entry Name
TNKS2_HUMAN

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Product Notes

The TNKS2 tnks2 (Catalog #AAA286007) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1126-1156. The Tnks 2 Antibody (C-term) reacts with Human, mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Tnks 2 can be used in a range of immunoassay formats including, but not limited to, FCM/FACS (Flow Cytometry), ELISA, WB (Western Blot). Researchers should empirically determine the suitability of the TNKS2 tnks2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tnks 2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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