WB (Western Blot)
(Western blot analysis of TNPO3 expression in Jurkat cell lysate with TNPO3 antibody at (A) 1 and (B) 2 μg/ml.)
Rabbit TNPO3 Polyclonal Antibody | anti-TNPO3 antibody
TNPO3 Antibody
Gene Names
TNPO3; IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
TNPO3 Antibody is affinity chromatography purified via peptide column.
Synonyms
TNPO3, Antibody; TNPO3 Antibody; TNPO3; IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2; Transportin-3; Importin-12; Imp12; transportin 3; anti-TNPO3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
TNPO3 Antibody is affinity chromatography purified via peptide column.
Form/Format
Liquid
Concentration
1 mg/mL (varies by lot)
Sequence Length
957
Applicable Applications for anti-TNPO3 antibody
WB (Western Blot), ELISA
Conjugate
Unconjugated
Immunogen
TNPO3 antibody was raised against a 18 amino acid synthetic peptide from near the amino terminus of human TNPO3.
Buffer
TNPO3 Antibody is supplied in PBS containing 0.02% sodium azide.
Preparation and Storage
TNPO3 antibody can be stored at 4 degree C for three months and -20 degree C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
WB (Western Blot)
(Western blot analysis of TNPO3 expression in Jurkat cell lysate with TNPO3 antibody at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of TNPO3 expression in Jurkat cell lysate with TNPO3 antibody at (A) 1 and (B) 2 μg/ml.)
WB (Western Blot)
(Western blot analysis of TNPO3 in rat liver tissue lysate with TNPO3 antibody at (A) 1 and (B) 2 μg/mL.)
WB (Western Blot)
(Western blot analysis of TNPO3 in rat liver tissue lysate with TNPO3 antibody at (A) 1 and (B) 2 μg/mL.)
Related Product Information for anti-TNPO3 antibody
TNPO3 Antibody: TNPO3 is a member of the importin beta/transportin family of nuclear import receptors and is specific for the essential splicing factors termed SR proteins, binding specifically and directly to the arginine/serine (RS)-rich domains of these proteins. Further experiments demonstrated that this interaction occurs only when these RS domains are phosphorylated. More recently, TNPO3 was identified as an HIV dependency factor (HDF) and that depletion of TNPO3 resulted in HIV inhibition after reverse transcription but before integration, suggesting that TNPO3 may be an important drug target in HIV treatment. At least three isoforms of TNPO3 are known to exist.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
97,372 Da
NCBI Official Full Name
transportin 3, isoform CRA_a
NCBI Official Synonym Full Names
transportin 3
NCBI Official Symbol
TNPO3
NCBI Official Synonym Symbols
IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2
NCBI Protein Information
transportin-3; imp12; importin 12; transportin-SR; limb girdle muscular dystrophy 1F (autosomal dominant)
UniProt Protein Name
Transportin-3
UniProt Gene Name
TNPO3
UniProt Synonym Gene Names
IPO12; Imp12; TRN-SR
UniProt Entry Name
TNPO3_HUMAN
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Product Notes
The TNPO3 tnpo3 (Catalog #AAA40376) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNPO3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TNPO3 can be used in a range of immunoassay formats including, but not limited to, WB (Western Blot), ELISA. Researchers should empirically determine the suitability of the TNPO3 tnpo3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNPO3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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