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product-image-AAA169658_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochmistry of paraffin-embedded rat liver using TOR1A antibody at dilution of 1:200(400x lens))

Rabbit TOR1A Polyclonal Antibody | anti-TOR1A antibody

TOR1A Antibody

Gene Names
TOR1A; DQ2; DYT1
Reactivity
Human, Mouse, Rat
Applications
Immunohistochemistry, Western Blot
Purity
Antigen affinity purification
Synonyms
TOR1A, Antibody; TOR1A Antibody; DQ2; DYT1; TorsinA; anti-TOR1A antibody
Ordering
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
1mg/mL (varies by lot)
Sequence Length
332
Applicable Applications for anti-TOR1A antibody
IHC (Immunohistochemistry), WB (Western Blot)
Immunogen
Recombinant protein of human TOR1A
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-19482 / sc-19483 / sc-33606
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

IHC (Immunohistochemisry)

(Immunohistochmistry of paraffin-embedded rat liver using TOR1A antibody at dilution of 1:200(400x lens))

product-image-AAA169658_IHC11.jpg IHC (Immunohistochemisry) (Immunohistochmistry of paraffin-embedded rat liver using TOR1A antibody at dilution of 1:200(400x lens))

IHC (Immunohiostchemistry)

(Immunohistochemistry of paraffin-embedded human normal breast using TOR1A antibody at dilution of 1:200(400x lens))

product-image-AAA169658_IHC13.jpg IHC (Immunohiostchemistry) (Immunohistochemistry of paraffin-embedded human normal breast using TOR1A antibody at dilution of 1:200(400x lens))

WB (Western Blot)

(Western blot analysis of extracts of various cell lines, using TOR1A antibody.)

product-image-AAA169658_WB15.jpg WB (Western Blot) (Western blot analysis of extracts of various cell lines, using TOR1A antibody.)
Related Product Information for anti-TOR1A antibody
The neurological condition Dystonia is associated with sustained muscle contractions and abnormal posturing (1). TorsinA, torsinB, torp2A and torp3A belong to the family of ATPases associated with cellular activites (AAA+) and mutations in torsinA cause early onset dystonia (2). TorsinA has been shown to suppress intracellular protein aggregation in C. elegans and possesses chaperon activity. Interestingly, torsinA is highly expressed in dopaminergic neurons and associates with alpha-synuclein in Lewy bodies, which pathologically characterize Parkinson's Disease (3-5).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
22,135 Da
NCBI Official Full Name
torsin-1A
NCBI Official Synonym Full Names
torsin family 1, member A (torsin A)
NCBI Official Symbol
TOR1A
NCBI Official Synonym Symbols
DQ2; DYT1
NCBI Protein Information
torsin-1A; dystonia 1 protein; dystonia 1, torsion (autosomal dominant; torsin A); torsin ATPase 1; torsin ATPase-1A; torsin family 1 member A
UniProt Protein Name
Torsin-1A
UniProt Gene Name
TOR1A
UniProt Synonym Gene Names
DQ2; DYT1; TA; TORA
UniProt Entry Name
TOR1A_HUMAN

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Product Notes

The TOR1A tor1a (Catalog #AAA169658) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TOR1A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TOR1A can be used in a range of immunoassay formats including, but not limited to, IHC (Immunohistochemistry), WB (Western Blot). Researchers should empirically determine the suitability of the TOR1A tor1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TOR1A, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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